| Autor: |
Feng LZ; Division of Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China., Peng ZB; Division of Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China., Wang DY; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China., Yang P; Infectious Disease & Endemic Disease Control, Beijing Center forDisease Prevention and Control, Beijing 100013, China., Yang J; School of Public Health, Fudan University, Shanghai 200032, China., Zhang YY; Institute for Immunization Prevention and Planning, Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, China., Chen J; Institute for Communicable Disease Control and Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China., Jiang SQ; Department for Immunization Prevention and Planning, Nanshan District Center for Disease Control and Prevention, Shenzhen 518055., Xu LL; Institute for Communicable Disease Control and Prevention, Qinghai Center for Disease Prevention and Control, Xining 810007, China., Kang M; Institute for Communicable Disease Control and Prevention, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China., Chen T; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China., Zheng YM; Division of Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China., Zheng JD; Division of Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China., Qin Y; Division of Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China., Zhao MJ; Department for Emergency Management, Jinan Center for Disease Control and Prevention, Jinan 250021, China., Tan YY; Department for Communicable Disease Control and Prevention, Suzhou Center for Disease Control and Prevention, Suzhou 215004, China., Li ZJ; Division of Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China., Feng ZJ; Chinese Center for Disease Control and Prevention, Beijing 102206, China. |
| Abstrakt: |
Seasonal influenza vaccination is the most effective way to prevent influenza virus infection and its complications. Currently, China has licensed trivalent (IIV3) and quadrivalent inactivated influenza vaccine (IIV4), including split-virus influenza vaccine and subunit vaccine. In most parts of China, influenza vaccine is a category Ⅱ vaccine, which means influenza vaccination is voluntary, and recipients need to pay for it. To strengthen the technical guidance for prevention and control of influenza and the operational research on influenza vaccination in China, the National Immunization Advisory Committee (NIAC), Influenza Vaccine Technical Working Group (TWG), updated the 2014 technical guidelines and compiled the " Technical guidelines for seasonal influenza vaccination in China ( 2018 - 2019 )" , based on most recent existing scientific evidences. The main updates include: epidemiology and disease burden of influenza, types of influenza vaccines, northern hemisphere influenza vaccination composition for the 2018-2019 season, and, IIV3 and IIV4 vaccines'major immune responses, durability of immunity, immunogenicity, vaccine efficacy, effectiveness, safety, cost-effectiveness and cost-benefit. The recommendations include: Points of Vaccination clinics (PoVs) should provide influenza vaccination to all persons aged 6 months and above who are willing to be vaccinated and do not have contraindications. No preferential recommendation is made for any influenza vaccine product for persons who can accept ≥1 licensed, recommended, and appropriate products. To decrease the risk of severe infections and complications due to influenza virus infection among high risk groups, the recommendations prioritize seasonal influenza vaccination for children aged 6-60 months, adults ≥60 years of age, persons with specific chronic diseases, healthcare workers, the family members and caregivers of infants <6 months of age, and pregnant women or women who plan to pregnant during the influenza season. Children aged 6 months to 8 years old require 2 doses of influenza vaccine administered a minimum of 4 weeks apart during their first season of vaccination for optimal protection. If they were vaccinated in previous influenza season, 1 dose is recommended. People ≥ 9 years old require 1 dose of influenza vaccine. It is recommended that people receive their influenza vaccination by the end of October. Influenza vaccination should be offered as soon as the vaccination is available. Influenza vaccination should continue to be available for those unable to be vaccinated before the end of October during the whole season. Influenza vaccine is also recommended for use in pregnant women during any trimester. These guidelines are intended for CDC members who are working on influenza control and prevention, PoVs members, healthcare workers from the departments of pediatrics, internal medicine, and infectious diseases, and members of maternity and child care institutions at all levels. |
