Pectin gelling in acidic gastric condition increases rheological properties of gastric digesta and reduces glycaemic response in mice.

Autor: Khramova DS; Institute of Physiology of Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS, 50, Pervomaiskaya str., 167982 Syktyvkar, Russia. Electronic address: dkhramova@gmail.com., Vityazev FV; Institute of Physiology of Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS, 50, Pervomaiskaya str., 167982 Syktyvkar, Russia., Saveliev NY; Institute of Physiology of Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS, 50, Pervomaiskaya str., 167982 Syktyvkar, Russia., Burkov AA; Vyatka State University, 36, Moskovskaya str., 610000, Kirov, Russia., Beloserov VS; Vyatka State University, 36, Moskovskaya str., 610000, Kirov, Russia., Martinson EA; Vyatka State University, 36, Moskovskaya str., 610000, Kirov, Russia., Litvinets SG; Vyatka State University, 36, Moskovskaya str., 610000, Kirov, Russia., Popov SV; Institute of Physiology of Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS, 50, Pervomaiskaya str., 167982 Syktyvkar, Russia.
Jazyk: angličtina
Zdroj: Carbohydrate polymers [Carbohydr Polym] 2019 Feb 01; Vol. 205, pp. 456-464. Date of Electronic Publication: 2018 Oct 25.
DOI: 10.1016/j.carbpol.2018.10.053
Abstrakt: The rheological characteristics and transit time of gastric digesta and the postprandial glycaemic response in mice orally administered with water (control) or pectin solutions supplemented (AP-Ca) or not supplemented (AP) with CaCO 3 were elucidated. AP and AP-Ca increased viscosity, storage and loss moduluses (G' and G'') of mice gastric digesta. The gelling capacity of AP-Ca in acidic gastric conditions appeared to provide a greater enhancement of gastric digesta viscosity compared with AP. The postprandial blood glucose concentration was lower in mice orally administered with AP or AP-Ca compared with control mice. The transit time of gastric digesta and the blood glucose concentration were affected in mice orally administered with AP during the early postprandial period. The effect of AP-Ca on the gastric digesta rheology and transit time was stronger than that of AP. Both of the pectin solutions failed to reduce food intake in mice.
(Copyright © 2018 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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