Neurophysiological Evaluation of a Customizable μECoG-based Wireless Brain Implant.

Autor: Gkogkidis CA, Bentler C, Wang X, Gierthmuehlen M, Scheiwe C, Schmitz HC, Haberstroh J, Stieglitz T, Ball T
Jazyk: angličtina
Zdroj: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2018 Jul; Vol. 2018, pp. 2953-2956.
DOI: 10.1109/EMBC.2018.8513044
Abstrakt: The number of implantable bidirectional neural interfaces available for neuroscientific research applications is still limited, despite the rapidly increasing number of customized components. We previously reported on how to translate available components into "ready-to-use" wireless implantable systems utilizing components off-the-shelf (COTS). The aim of the present study was to verify the viability of a micro-electrocorticographic ($\mu $ECoG) device built by this approach. Functionality for both neural recording and stimulation was evaluated in an ovine animal model using acoustic stimuli and cortical electrical stimulation, respectively. We show that auditory evoked responses were reliably recorded in both time and frequency domain and present data that demonstrates the cortical electrical stimulation functionality. The successful recording of neuronal activity suggests that the device can compete with existing implantable systems as a neurotechnological research tool.
Databáze: MEDLINE