Is the Montreal Cognitive Assessment (MoCA) screening superior to the Mini-Mental State Examination (MMSE) in the detection of mild cognitive impairment (MCI) and Alzheimer's Disease (AD) in the elderly?

Autor:	Pinto TCC; Post-graduate program in Neuropsychiatry and Behavioral Science at the Federal University of Pernambuco,Recife,Brazil., Machado L; Post-graduate program in Neuropsychiatry and Behavioral Science at the Federal University of Pernambuco,Recife,Brazil., Bulgacov TM; Post-graduate program in Neuropsychiatry and Behavioral Science at the Federal University of Pernambuco,Recife,Brazil., Rodrigues-Júnior AL; Post-graduate program in Neuropsychiatry and Behavioral Science at the Federal University of Pernambuco,Recife,Brazil., Costa MLG; Post-graduate program in Neuropsychiatry and Behavioral Science at the Federal University of Pernambuco,Recife,Brazil., Ximenes RCC; Post-graduate program in Neuropsychiatry and Behavioral Science at the Federal University of Pernambuco,Recife,Brazil., Sougey EB; Post-graduate program in Neuropsychiatry and Behavioral Science at the Federal University of Pernambuco,Recife,Brazil.
Jazyk:	angličtina
Zdroj:	International psychogeriatrics [Int Psychogeriatr] 2019 Apr; Vol. 31 (4), pp. 491-504. Date of Electronic Publication: 2018 Nov 14.
DOI:	10.1017/S1041610218001370
Abstrakt:	ABSTRACTObjective:To compare the accuracy of Mini-Mental State Examination (MMSE) and of the Montreal Cognitive Assessment (MoCA) in tracking mild cognitive impairment (MCI) and Alzheimer's Disease (AD). Method: A Systematic review of the PubMed, Bireme, Science Direct, Cochrane Library, and PsycInfo databases was conducted. Using inclusion and exclusion criteria and staring with 1,629 articles, 34 articles were selected. The quality of the selected research was evaluated through the Quality Assessment of Diagnostic Accuracy Studies 2 tool (QUADAS-2). Result: More than 80% of the articles showed MoCA to be superior to MMSE in discriminating between individuals with mild cognitive impairment and no cognitive impairment. The area under the curve varied from 0.71 to 0.99 for MoCA, and 0.43 to 0.94 for MMSE, when evaluating the ability to discriminate MCI in the cognitively healthy elderly individuals, and 0.87 to 0.99 and 0.67 to 0.99, respectively, when evaluating the detection of AD. The AUC mean value for MoCA was significantly larger compared to the MMSE in discriminating MCI from control [0.883 (CI 95% 0.855-0.912) vs MMSE 0.780 (CI 95% 0.740-0.820) p < 0.001]. Conclusion: The screening tool MoCA is superior to MMSE in the identification of MCI, and both tests were found to be accurate in the detection of AD.
Databáze:	MEDLINE
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