Benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community.

Autor: Johnson CF; Specialist Mental Health and Prescribing Support Pharmacist Primary Care, Pharmacy and Prescribing Support Unit, NHS Greater Glasgow and Clyde, West Glasgow Ambulatory Care Hospital. Glasgow (United Kingdom). c.johnson2@nhs.net., Nassr OA; College of Pharmacy, Al-Mustansiriya University, Baghdad (Iraq). ola.nassr2014@yahoo.com., Harpur C; Registrar in Psychiatry. Dykebar Hospital, NHS Greater Glasgow & Clyde. Paisley (United Kingdom). catherine.harpur@nhs.net., Kenicer D; Consultant Psychiatrist. Riverside Community Mental Health Team, NHS Greater Glasgow & Clyde. Glasgow (United Kingdom). David.Kenicer@ggc.scot.nhs.uk., Thom A; Consultant Psychiatrist. Dykebar Hospital, NHS Greater Glasgow & Clyde. Paisley (United Kingdom). Alex.Thom@ggc.scot.nhs.uk., Akram G; Lecturer and Specialist Psychiatric Pharmacist, Strathclyde Institute of Pharmacy & Biomedical Sciences. University of Strathclyde. Glasgow (United Kingdom). gazala.akram@strath.ac.uk.
Jazyk: angličtina
Zdroj: Pharmacy practice [Pharm Pract (Granada)] 2018 Jul-Sep; Vol. 16 (3), pp. 1256. Date of Electronic Publication: 2018 Sep 26.
DOI: 10.18549/PharmPract.2018.03.1256
Abstrakt: Background: Benzodiazepine and z-hypnotic prescribing has slowly decreased over the past 20 years, however long-term chronic prescribing still occurs and is at odds with prescribing guidance.
Objectives: To identify the pattern of benzodiazepine and z-hypnotic prescribing in psychiatric inpatients at discharge and 12 months post-discharge.
Methods: Retrospective observational longitudinal cohort study of patients admitted to two adult psychiatric wards between June and November 2012 (inclusive) who were discharged with a prescription for a benzodiazepine or z-hypnotic drug. Routinely collected prescription data available from NHS Scotland Prescribing Information System was used to identify and follow community prescribing of benzodiazepine and z-hypnotics for a 12 month period post-discharge. Data were entered in Excel ® and further analysed using SPSS 23. Ethical approval was not required for this service evaluation however Caldicott Guardian approval was sought and granted.
Results: Eighty patients were admitted during the study period however only those patients with a single admission were included for analysis (n=74). Thirty per cent (22/74) of patients were prescribed a benzodiazepine or z-hypnotics at discharge; 14 of whom received 'long-term' benzodiazepine and z-hypnotics i.e. continued use over the 12 month period. Seven patients received a combination of anxiolytics and hypnotics (e.g., diazepam plus temazepam or zopiclone). Long-term use was associated with a non-significant increase in median benzodiazepine or z-hypnotic dose, expressed as diazepam equivalents.
Conclusions: One in three patients were prescribed a benzodiazepine or z-hypnotics at discharge with 1 in 5 receiving continuous long-term treatment (prescriptions) for 12 months post-discharge. As chronic long-term B-Z prescribing and use still remains an issue, future strategies using routine patient-level prescribing data may support prescribers to review and minimise inappropriate long-term prescribing.
Competing Interests: CONFLICT OF INTEREST None.
Databáze: MEDLINE