Autor: |
Gil MJ, Serrano S, Manzano MS, Cuadrado ML, Góméz E, Rábano A |
Jazyk: |
angličtina |
Zdroj: |
Clinical neuropathology [Clin Neuropathol] 2019 Jan/Feb; Vol. 38 (1), pp. 8-13. |
DOI: |
10.5414/NP301122 |
Abstrakt: |
Argyrophilic grain disease (AgD) is a frequent late-onset 4R tauopathy of old age characterized by the presence of profuse spindle-shaped argyrophilic grains (AGs). It is a neurodegenerative disorder that is clinically characterized by a slow progressive amnestic mild cognitive impairment similar to Alzheimer's disease. In rare instances, it is characterized as a behavioral-variant frontotemporal dementia (bv-FTD). In this study, we report a case with typical clinical and neuroimaging features of bv-FTD, who had autopsy findings consistent with a definitive diagnosis of AgD. We suggest that AgD might be included in the differential diagnosis of patients presenting with bv-FTD.
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Databáze: |
MEDLINE |
Externí odkaz: |
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