Surgical Feasibility of a One-Stage Cell-Based Arthroscopic Procedure for Meniscus Regeneration: A Cadaveric Study.

Autor: Hagmeijer MH; 1 Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Vonk LA; 1 Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Kouwenhoven JW; 1 Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Custers RJH; 1 Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Bleys RL; 2 Department of Anatomy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Krych AJ; 3 Department of Orthopedic Surgery and Sports Medicine, Mayo Clinic, Rochester, Minnesota., Saris DBF; 1 Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; 3 Department of Orthopedic Surgery and Sports Medicine, Mayo Clinic, Rochester, Minnesota.; 4 MIRA Institute for Technical Medicine, University Twente, Enschede, The Netherlands.
Jazyk: angličtina
Zdroj: Tissue engineering. Part C, Methods [Tissue Eng Part C Methods] 2018 Dec; Vol. 24 (12), pp. 688-696.
DOI: 10.1089/ten.TEC.2018.0240
Abstrakt: Impact Statement: Meniscus injury remains the most common indication for orthopedic surgery, but loss of functioning meniscus tissue is strongly correlated with development of early osteoarthritis. However, current clinical options for tissue engineering of the meniscus are limited. This study demonstrates the feasibility of combining human meniscus cells with mesenchymal stromal cells to enhance a meniscus scaffold for meniscus regeneration in a one-stage solution for partial meniscal deficiency.
Databáze: MEDLINE