[Effect of metronidazole and local irradiation of the tumor on paramagnetic metal complexes of the liver and tumor tissues].

Autor: Zhumabaeva TT, Kudriavtsev ME, Voronina SS, Kuropteva ZV
Jazyk: ruština
Zdroj: Radiobiologiia [Radiobiologiia] 1987 May-Jun; Vol. 27 (3), pp. 384-9.
Abstrakt: A study was made of changes in the intensity of the ESR signals in tissues of sarcoma-37 and liver of mice after radiation of the tumor, administration of metronidazole, and after the combined effect of the two factors. The most pronounced changes in the ESR signals were induced by metronidazole. An appreciable increase in the content of nitrosyl complexes in the tumor was noted after the combined effect of metronidazole and radiation which was indicative of the radiation-induced formation of a large number of metronidazole anion-radicals in the tumor.
Databáze: MEDLINE