Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL knowledge hub project.

Autor: Correa-Pérez A; Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain. Electronic address: Andrea.correa@salud.madrid.org., Abraha I; Geriatria, Accettazione geriatrica e Centro di ricerca per l'invecchiamento, Italian National Research Center on Aging (IRCCS- INRCA), Ancona, Italy., Cherubini A; Geriatria, Accettazione geriatrica e Centro di ricerca per l'invecchiamento, Italian National Research Center on Aging (IRCCS- INRCA), Ancona, Italy., Collinson A; Institute of Health and Community, University of Plymouth, United Kingdom., Dardevet D; Université Clermont Auvergne, INRA, UNH, Centre de Recherche en Nutrition Humaine (CRNH), Clermont-Ferrand, France., de Groot LCPGM; Division of Human Nutrition and Health, Wageningen University. Wageningen, the Netherlands., de van der Schueren MAE; Department of Nutrition and health, HAN University of Applied Sciences, Nijmegen, Department of Nutrition and Dietetics, VU University Medical Center, Amsterdam, the Netherlands., Hebestreit A; Leibniz Institute for Prevention Research and Epidemiology - BIPS. Bremen, Germany., Hickson M; Institute of Health and Community, University of Plymouth, United Kingdom., Jaramillo-Hidalgo J; Servicio de Geriatría, Hospital Central de la Cruz Roja San José y Santa Adela, Madrid, Spain., Lozano-Montoya I; Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain., O'Mahony D; Department of Geriatric Medicine, Cork University Hospital, Cork, Ireland., Soiza RL; Department of Medicine for the Elderly, NHS Grampian, Aberdeen, United Kingdom., Visser M; Department of Health Sciences, Vrije Universiteit Amsterdam, the Nederlands., Volkert D; Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nuremberg, Germany., Wolters M; Leibniz Institute for Prevention Research and Epidemiology - BIPS. Bremen, Germany., Cruz Jentoft AJ; Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain.
Jazyk: angličtina
Zdroj: Ageing research reviews [Ageing Res Rev] 2019 Jan; Vol. 49, pp. 27-48. Date of Electronic Publication: 2018 Nov 02.
DOI: 10.1016/j.arr.2018.10.011
Abstrakt: Introduction: We aimed to perform a review of SRs of non-pharmacological interventions in older patients with well-defined malnutrition using relevant outcomes agreed by a broad panel of experts.
Methods: PubMed, Cochrane, EMBASE, and CINHAL databases were searched for SRs. Primary studies from those SRs were included. Quality assessment was undertaken using Cochrane and GRADE criteria.
Results: Eighteen primary studies from seventeen SRs were included. Eleven RCTs compared oral nutritional supplementation (ONS) with usual care. No beneficial effects of ONS treatment, after performing two meta-analysis in body weight changes (six studies), mean difference: 0.59 (95%CI -0.08, 1.96) kg, and in body mass index changes (two studies), mean difference: 0.31 (95%CI -0.17, 0.79) kg/m2 were found. Neither in MNA scores, muscle strength, activities of daily living, timed Up&Go, quality of life and mortality. Results of other intervention studies (dietary counselling and ONS, ONS combined with exercise, nutrition delivery systems) were inconsistent. The overall quality of the evidence was very low due to risk of bias and small sample size.
Conclusions: This review has highlighted the lack of high quality evidence to indicate which interventions are effective in treating malnutrition in older people. High quality research studies are urgently needed in this area.
(Copyright © 2018 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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