Mapping rural-urban disparities in late-stage cancer with high-resolution rurality index and GWR.

Autor: Mao L; Department of Geography, University of Florida, P.O. box 117315, 3141 Turlington Hall, Gainesville, FL 32611 USA. Electronic address: liangmao@ufl.edu., Yang J; Department of Geography, University of Florida, P.O. box 117315, 3141 Turlington Hall, Gainesville, FL 32611 USA., Deng G; Department of Geography, University of Florida, P.O. box 117315, 3141 Turlington Hall, Gainesville, FL 32611 USA.
Jazyk: angličtina
Zdroj: Spatial and spatio-temporal epidemiology [Spat Spatiotemporal Epidemiol] 2018 Aug; Vol. 26, pp. 15-23. Date of Electronic Publication: 2018 May 07.
DOI: 10.1016/j.sste.2018.04.001
Abstrakt: Effects of urban/rural residence on late-stage cancer have long been explored, but remained controversial. Spatial granularity of rural definition, temporal change of rurality, and local variability of such effects may contribute to inconsistent findings, but they have not been fully addressed. We proposed a spatially resolved and temporally comparable rurality index and a geographically weighted regression approach to re-examine this question. Taking Florida as an example, our analyses show that rural effects on late-stage cancer vary dramatically over locations (600-m cells). The odds ratios range from 0.9 to 1.10, and imply that one degree of rurality can increase/decrease local risk of late-stage cancer by up to 10%. Our study is an early attempt to explore local effects of rurality on cancer at a fine spatial scale, and reveals interesting patterns hidden by global multi-level analysis. The new framework and findings can better inform precision interventions to mitigate cancer disparities.
(Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE