The presence of fecal test soil protects bacteria during cleaning/disinfection.

Autor: Nandy P; Laboratory of Microbiology and Infection Control, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, 20993., Gonzalez EA; Laboratory of Microbiology and Infection Control, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, 20993., Lucas AD; Laboratory of Microbiology and Infection Control, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, 20993., Hitchins VM; Laboratory of Microbiology and Infection Control, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, 20993.
Jazyk: angličtina
Zdroj: Journal of biomedical materials research. Part B, Applied biomaterials [J Biomed Mater Res B Appl Biomater] 2019 Jul; Vol. 107 (5), pp. 1706-1710. Date of Electronic Publication: 2018 Nov 02.
DOI: 10.1002/jbm.b.34263
Abstrakt: Reusable medical devices (RMDs) must be reprocessed between uses to render them safe for each use and each patient. Cleaning used devices removes organic and inorganic soil making them either safe for reuse or ready for disinfection/sterilization depending on the device. Although cleaning is an important step in a RMD's life cycle, it is not always a priority during device design. In addition, when performing cleaning validation, it is recommended that the manufacturer takes into consideration, what the most appropriate or worst case conditions are in terms of type of soil or the presence of bacteria. This study compared the ability of three different cleaning/disinfecting agents (water, alcohol, and bleach) to remove bacteria and fecal test soil from two different polymers: polypropylene and ultrahigh molecular weight polyethylene (UHMWPE) with two different roughness. There were some differences in the effects of the cleaning/disinfecting agents, the materials, and the roughness depending on the particular circumstances. However, the most consistent effect on the removal of bacteria was the presence of soil, which protected the bacteria from being removed. Conversely, the presence of bacteria played little role in the removal of soil. Although the interactions between material type and roughness, soil type, and bacteria are complicated, they should be taken into account during device design and reprocessing validation to create a device that is easy and safe to use. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 107B: 1706-1710, 2019.
(Published 2018. This article is a U.S. Government work and is in the public domain in the USA.)
Databáze: MEDLINE
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