More than Just a "Motor": Recent Surprises from the Frontal Cortex.

Autor:	Ebbesen CL; Skirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, New York 10016, christian.ebbesen@nyumc.org.; Center for Neural Science, New York University, New York, New York 10003., Insanally MN; Skirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, New York 10016.; Center for Neural Science, New York University, New York, New York 10003., Kopec CD; Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey 08544., Murakami M; Department of Neurophysiology, Division of Medicine, University of Yamanashi, Chuo, Yamanashi 409-3898, Japan., Saiki A; Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.; Department of Neurobiology, Northwestern University, Evanston, Illinois 60208., Erlich JC; New York University Shanghai, Shanghai, China 200122.; NYU-ECNU Institute for Brain and Cognitive Science at NYU Shanghai, Shanghai, China 200062, and.; Shanghai Key Laboratory of Brain Functional Genomics (Ministry of Education), East China Normal University, Shanghai, China 200062.
Jazyk:	angličtina
Zdroj:	The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2018 Oct 31; Vol. 38 (44), pp. 9402-9413.
DOI:	10.1523/JNEUROSCI.1671-18.2018
Abstrakt:	Motor and premotor cortices are crucial for the control of movements. However, we still know little about how these areas contribute to higher-order motor control, such as deciding which movements to make and when to make them. Here we focus on rodent studies and review recent findings, which suggest that-in addition to motor control-neurons in motor cortices play a role in sensory integration, behavioral strategizing, working memory, and decision-making. We suggest that these seemingly disparate functions may subserve an evolutionarily conserved role in sensorimotor cognition and that further study of rodent motor cortices could make a major contribution to our understanding of the evolution and function of the mammalian frontal cortex. (Copyright © 2018 the authors 0270-6474/18/389402-12$15.00/0.)
Databáze:	MEDLINE
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