MRI findings of metronidazole neurotoxicity in a pediatric patient with chronic diarrhea.

Autor: Yazdani RM; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA., Kayfan S; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA., Cao J; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA., Clarke RL; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA., Pfeifer CM; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.
Jazyk: angličtina
Zdroj: Radiology case reports [Radiol Case Rep] 2018 Oct 22; Vol. 14 (1), pp. 75-78. Date of Electronic Publication: 2018 Oct 22 (Print Publication: 2019).
DOI: 10.1016/j.radcr.2018.09.026
Abstrakt: Neurotoxicity is a rare side effect of metronidazole therapy. Shown here are findings of metronidazole toxicity in a patient, who received chronic metronidazole as prophylaxis for pseudomembranous colitis following bowel resection as an infant. Findings depicted include increased T2 signal in the dentate nuclei and brainstem. Discontinuing the medication resulted in reversal of the findings.
Databáze: MEDLINE