Childhood-Onset Movement Disorders: A Clinical Series of 606 Cases.

Autor: Bäumer T; Department of Paediatric and Adult Movement Disorders and Neuropsychiatry Institute of Neurogenetics University of Lübeck Lübeck Germany.; Department of Neurology University Medical Center Hamburg-Eppendorf Hamburg Germany., Sajin V; Department of Paediatric and Adult Movement Disorders and Neuropsychiatry Institute of Neurogenetics University of Lübeck Lübeck Germany.; Institute of Neurology and Neurosurgery Chișinău Republic of Moldova., Münchau A; Department of Paediatric and Adult Movement Disorders and Neuropsychiatry Institute of Neurogenetics University of Lübeck Lübeck Germany.; Department of Neurology University Medical Center Hamburg-Eppendorf Hamburg Germany.
Jazyk: angličtina
Zdroj: Movement disorders clinical practice [Mov Disord Clin Pract] 2016 Jul 23; Vol. 4 (3), pp. 437-440. Date of Electronic Publication: 2016 Jul 23 (Print Publication: 2017).
DOI: 10.1002/mdc3.12399
Abstrakt: The aim of this work is to report the distribution of clinical phenomenology, demographic variables, and delay of diagnosis in a cohort of patients with childhood-onset movement disorders. Personally examined patients with childhood-onset movement disorders apart from those with cerebral palsy are reported. A total of 606 patients were included. The majority had tic disorders (346; 57%) followed by dystonia (72; 12%); other movement disorders were less frequent (<5%). Mean onset age of patients with tics was 7.4 years ± 3.8 standard deviation; mean delay of diagnosis was 9.9 ± 11 years. Mean onset age of other movement disorders was 8.6 ± 5.7 years; mean delay of diagnosis was 11.1 ± 12.5 years. Psychogenic movement disorders had a later onset than all other movement disorders ( P < 0.01) apart from tremor and "other movement disorders." Dystonias had a longer delay of diagnosis than psychogenic movement disorders ( P < 0.038). The diagnostic delay of childhood-onset movement disorders is considerable, indicating that they are probably under-recognized.
Databáze: MEDLINE
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