Multi-ethnic variations in the practice of oral cancer risk habits in a developing country.

Autor: Ghani WMN; Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia., Razak IA; Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.; Faculty of Dentistry, MAHSA University, Selangor, Malaysia., Doss JG; Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.; Department of Community Oral Health and Clinical Prevention, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia., Yang YH; School of Pharmacy, Kaohsiung Medical University, Kaohsiung City, Taiwan., Rahman ZAA; Department of Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia., Ismail SM; Department of Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia., Abraham MT; Oral Health Division, Ministry of Health, Federal Government Administrative Centre, Putrajaya, Malaysia., Wan Mustafa WM; Faculty of Dentistry, MAHSA University, Selangor, Malaysia., Tay KK; Oral Health Division, Ministry of Health, Federal Government Administrative Centre, Putrajaya, Malaysia., Zain RB; Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.; Faculty of Dentistry, MAHSA University, Selangor, Malaysia.
Jazyk: angličtina
Zdroj: Oral diseases [Oral Dis] 2019 Mar; Vol. 25 (2), pp. 447-455. Date of Electronic Publication: 2018 Nov 08.
DOI: 10.1111/odi.12995
Abstrakt: Objective: To elucidate ethnic variations in the practice of oral cancer risk habits in a selected Malaysian population.
Methods: This retrospective case-control study involves 790 cases of cancers of the oral cavity and 450 controls presenting with non-malignant oral diseases, recruited from seven hospital-based centres nationwide. Data on risk habits (smoking, drinking, chewing) were obtained using a structured questionnaire via face-to-face interviews. Multiple logistic regression was used to determine association between risk habits and oral cancer risk; chi-square test was used to assess association between risk habits and ethnicity. Population attributable risks were calculated for all habits.
Results: Except for alcohol consumption, increased risk was observed for all habits; the highest risk was for smoking + chewing + drinking (aOR 22.37 95% CI 5.06, 98.95). Significant ethnic differences were observed in the practice of habits. The most common habit among Malays was smoking (24.2%); smoking + drinking were most common among Chinese (16.8%), whereas chewing was the most prevalent among Indians (45.2%) and Indigenous people (24.8%). Cessation of chewing, smoking and drinking is estimated to reduce cancer incidence by 22.6%, 8.5% and 6.9%, respectively.
Conclusion: Ethnic variations in the practice of oral cancer risk habits are evident. Betel quid chewing is the biggest attributable factor for this population.
(© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved.)
Databáze: MEDLINE
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