Long working hours, anthropometry, lung function, blood pressure and blood-based biomarkers: cross-sectional findings from the CONSTANCES study.

Autor:	Virtanen M; Stress Research Institute, Stockholm University, Stockholm, Sweden.; Department of Public Health and Caring Sciences, University of Uppsala, Uppsala, Sweden., Magnusson Hansson L; Stress Research Institute, Stockholm University, Stockholm, Sweden., Goldberg M; Population-Based Epidemiologic Cohorts Unit, Inserm UMS 011, Villejuif, France.; Faculty of Medicine, Paris Descartes University, Paris, France., Zins M; Population-Based Epidemiologic Cohorts Unit, Inserm UMS 011, Villejuif, France.; Faculty of Medicine, Paris Descartes University, Paris, France., Stenholm S; Department of Public Health, University of Turku and Turku University Hospital, Turku, Finland., Vahtera J; Department of Public Health, University of Turku and Turku University Hospital, Turku, Finland., Westerlund H; Stress Research Institute, Stockholm University, Stockholm, Sweden.; Department of Clinical Neuroscience, Division of Insurance Medicine, Karolinska Institutet, Stockholm, Sweden., Kivimäki M; Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Epidemiology and Public Health, University College London, London, UK.
Jazyk:	angličtina
Zdroj:	Journal of epidemiology and community health [J Epidemiol Community Health] 2019 Feb; Vol. 73 (2), pp. 130-135. Date of Electronic Publication: 2018 Oct 16.
DOI:	10.1136/jech-2018-210943
Abstrakt:	Background: Although long working hours have been shown to be associated with the onset of cardiometabolic diseases, the clinical risk factor profile associated with long working hours remains unclear. We compared the clinical risk profile between people who worked long hours and those who reported being never exposed to long hours. Methods: A cross-sectional study in 22 health screening centres in France was based on a random population-based sample of 75 709 participants aged 18-69 at study inception in 2012-2016 (the CONSTANCES study). The data included survey responses on working hours (never, former or current exposure to long working hours), covariates and standardised biomedical examinations including anthropometry, lung function, blood pressure and standard blood-based biomarkers. Results: Among men, long working hours were associated with higher anthropometric markers (Body Mass Index, waist circumference and waist:hip ratio), adverse lipid levels, higher glucose, creatinine, white blood cells and higher alanine transaminase (adjusted mean differences in the standardised scale between the exposed and unexposed 0.02-0.12). The largest differences were found for Body Mass Index and waist circumference. A dose-response pattern with increasing years of working long hours was found for anthropometric markers, total cholesterol, glucose and gamma-glutamyltransferase. Among women, long working hours were associated with Body Mass Index and white blood cells. Conclusion: In this study, men who worked long hours had slightly worse cardiometabolic and inflammatory profile than those who did not work long hours, especially with regard to anthropometric markers. In women, the corresponding associations were weak or absent. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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