Cellular Magnetic Resonance Imaging for Tracking Metastatic Cancer Cells in the Brain.

Autor:	Parkins KM; Robarts Research Institute, Western University, London, ON, Canada., Makela AV; Robarts Research Institute, Western University, London, ON, Canada., Hamilton AM; Robarts Research Institute, Western University, London, ON, Canada., Foster PJ; Robarts Research Institute, Western University, London, ON, Canada. pfoster@robarts.ca.
Jazyk:	angličtina
Zdroj:	Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2019; Vol. 1869, pp. 239-251.
DOI:	10.1007/978-1-4939-8805-1_20
Abstrakt:	Cellular magnetic resonance imaging (MRI) enables visualization of cells in vivo. This is accomplished by labeling cells with superparamagnetic iron oxide nanoparticles. Here, we describe the steps for labeling human cancer cells with iron for tracking them after injection into nude mice. We also provide details for validation of cell labeling, ultrasound guided intra-cardiac injection, and MRI.
Databáze:	MEDLINE
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