Management of calciphylaxis in a burn center: A case series and review of the literature.

Autor: Dado DN; Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, United States., Huang B; Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, United States., Foster DV; Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, United States., Nielsen JS; Burn Center, US Army Institute of Surgical Research, Fort Sam Houston, TX, United States., Gurney JM; Burn Center, US Army Institute of Surgical Research, Fort Sam Houston, TX, United States., Morrow BD; Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, United States; Uniformed Services University of the Health Sciences, Bethesda, MD, United States., Sharma K; Division of Nephrology, University of Texas Health Sciences Center, San Antonio, TX, United States., Chung KK; Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, United States; Uniformed Services University of the Health Sciences, Bethesda, MD, United States., Ainsworth CR; Burn Center, US Army Institute of Surgical Research, Fort Sam Houston, TX, United States; Uniformed Services University of the Health Sciences, Bethesda, MD, United States. Electronic address: craig.r.ainsworth.mil@mail.mil.
Jazyk: angličtina
Zdroj: Burns : journal of the International Society for Burn Injuries [Burns] 2019 Feb; Vol. 45 (1), pp. 241-246. Date of Electronic Publication: 2018 Oct 12.
DOI: 10.1016/j.burns.2018.09.008
Abstrakt: Calciphylaxis is a rare, necrotizing skin disorder usually associated with kidney disease, but also caused by many other systemic illnesses. This disease is associated with mortality rates as high as 80% at 1year. We present the demographic and clinical data of nine patients with calciphylaxis treated at our burn center over a 10year period. We review the literature on the clinical presentation, pathophysiology, diagnosis and treatment of this rare disease. We propose that these patients be treated similar to patients with thermal burn injury; meaning intensive wound care, surgical management, critical care and physical therapy. Burn centers are uniquely capable of caring for these incredibly complex patients due to their experience in managing patients with extensive skin and soft tissue defects, wounds and diseases.
(Copyright © 2018 Elsevier Ltd and ISBI. All rights reserved.)
Databáze: MEDLINE
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