First national iodine survey in Madagascar demonstrates iodine deficiency.

Autor: Randremanana RV; Unité épidémiologie, Institut Pasteur de Madagascar, Antananarivo, Madagascar., Bastaraud A; Laboratoire d'Hygiène des Aliments et de l'Environnement, Institut Pasteur de Madagascar, Antananarivo, Madagascar., Rabarijaona LP; Maison Commune des Nations Unies, UNICEF, Antananarivo, Madagascar., Piola P; Unité épidémiologie, Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Rakotonirina D; Service de Nutrition, Ministère de la Santé Publique, Antananarivo, Madagascar., Razafinimanana JO; Service de Nutrition, Ministère de la Santé Publique, Antananarivo, Madagascar., Ramangakoto MH; Service de Nutrition, Ministère de la Santé Publique, Antananarivo, Madagascar., Andriantsarafara L; Service Suivi et Evaluation, Office National de Nutrition, Antananarivo, Madagascar., Randriamasiarijaona H; Service de Nutrition, Ministère de la Santé Publique, Antananarivo, Madagascar., Tucker-Brown A; Maison Commune des Nations Unies, UNICEF, Antananarivo, Madagascar., Harimanana A; Unité épidémiologie, Institut Pasteur de Madagascar, Antananarivo, Madagascar., Namana S; Maison Commune des Nations Unies, UNICEF, Antananarivo, Madagascar.
Jazyk: angličtina
Zdroj: Maternal & child nutrition [Matern Child Nutr] 2019 Apr; Vol. 15 (2), pp. e12717. Date of Electronic Publication: 2018 Nov 08.
DOI: 10.1111/mcn.12717
Abstrakt: Universal salt iodization (USI) was adopted in Madagascar in 1995 within the framework of a worldwide policy to eliminate iodine deficiency disorders. Despite early USI adoption, there are no representative data on the iodine status of the Malagasy population. The aims of this study were to determine the iodine status of the Malagasy population and to assess the use of adequately iodized salt among households. We randomly sampled women of reproductive age (WRA) using a national, two-stage, stratified cross-sectional survey in 2014. Casual urine from WRA and salt samples from the household containing WRA were collected to measure urinary iodine concentration (UIC) and to assess household salt iodine content. Data from 1,721 WRA in 1,128 households were collected and analysed. The national median UIC was 46 μg L -1 (interquartile range [IQR]: 13-98 μg L -1 ), indicating a moderate iodine deficiency. The median UIC was 53 μg L -1 (IQR: 9-89 μg L -1 ) in pregnant women and 46 μg L -1 (IQR: 13-98 μg L -1 ) in non-pregnant women. The national median iodine concentration of household salt was 10 mg kg -1 (IQR: 6.3-15.8 mg kg -1 ) and 26.2% (95% CI [22.1, 31.0]) of households containing WRA used adequately iodized salt (≥15 mg kg -1 ). Women living in households with adequately iodized salt had higher median UIC (72 vs. 50 μg L -1 ). Iodine status was significantly lower among women from low socio-economic households. Madagascar's USI program needs to be revitalized. Implementing strategies to provide adequately iodized salt and enhancing iodized salt legislation to prevent severe complications resulting from iodine deficiency in the Malagasy population are essential.
(© 2018 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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