Effect of ibuprofen on the efficacy of inferior alveolar nerve block in patients with irreversible pulpitis: A meta-analysis.

Autor: de Geus JL; Department of Dentistry. State, University of Ponta Grossa, Ponta Grossa, PR, Brazil.; Department of Dentistry, Paulo Picanço School of Dentistry, Fortaleza, CE, Brazil.; Department of Restorative Dentistry, Guairacá Faculty, Guarapuava, PR, Brazil., Wambier LM; Department of Pediatric Dentistry, Positivo University, Curitiba, PR, Brazil., Boing TF; Department of Restorative Dentistry, Guairacá Faculty, Guarapuava, PR, Brazil., Loguercio AD; Department of Dentistry. State, University of Ponta Grossa, Ponta Grossa, PR, Brazil., Reis A; Department of Dentistry. State, University of Ponta Grossa, Ponta Grossa, PR, Brazil.
Jazyk: angličtina
Zdroj: Australian endodontic journal : the journal of the Australian Society of Endodontology Inc [Aust Endod J] 2019 Aug; Vol. 45 (2), pp. 246-258. Date of Electronic Publication: 2018 Oct 07.
DOI: 10.1111/aej.12306
Abstrakt: The aim of this study was to compare preventive ibuprofen administration to placebo on the efficacy of inferior alveolar nerve block in patients with irreversible pulpitis. A search was performed in PubMed, Scopus, Web of Science, LILACS, BBO, Cochrane Library, SIGLE, and grey literature. The risk of bias was evaluated through the Cochrane Collaboration's tool. The quality of evidence was assessed using the GRADE approach. Only seven studies remained for the meta-analysis. Administering ibuprofen before anaesthesia increased the success rate of injectable anaesthesia (RR = 1.79; 95% confidence interval (CI) 1.32-2.42; P = 0.0002) even in cases of symptomatic irreversible pulpitis (RR = 1.55; 95% CI 1.05-2.29; P = 0.03). The intensity of pain was lower for ibuprofen (standardised difference means (SMD) = -3.73; 95% CI -6.43 to -1.04; P = 0.007). Ibuprofen as premedication is beneficial for the success of inferior alveolar nerve block.
(© 2018 Australian Society of Endodontology Inc.)
Databáze: MEDLINE
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