Effectiveness of Mentha piperita Leaf Extracts against Oral Pathogens: An in vitro Study.

Autor:	Raghavan R; Department of Periodontology, Educare Institute of Dental Sciences, Malappuram, Kerala, India, Phone: +919349118552, e-mail: raghavan.rekha8@gmail.com., Devi MPS; Department of Periodontology, P.S.M. College of Dental Science & Research, Thrissur, Kerala, India., Varghese M; Department of Periodontology, P.S.M. College of Dental Science & Research, Thrissur, Kerala, India., Joseph A; Department of Periodontology, Educare Institute of Dental Sciences, Malappuram, Kerala, India., Madhavan SS; Department of Periodontology, Sree Anjaneya Institute of Dental Sciences, Kozhikode, Kerala, India., Sreedevi PV; Department of Conservative Dentistry and Endodontics, P.S.M. College of Dental Science & Research, Thrissur, Kerala, India.
Jazyk:	angličtina
Zdroj:	The journal of contemporary dental practice [J Contemp Dent Pract] 2018 Sep 01; Vol. 19 (9), pp. 1042-1046. Date of Electronic Publication: 2018 Sep 01.
Abstrakt:	Aim: The study aims to assess the Mentha piperita leaf extract's effectiveness against oral pathogens. Materials and Methods: The leaf extract of M. piperita was prepared using cold water method. The three microbial strains, i.e., Streptococcus mutans, Aggregatibacter actinomycetem-comitans, and Candida albicans were used as microbiological materials. Chlorhexidine 0.2% was used as positive control. The digital caliper was used to measure the zone of inhibition to know the antimicrobial activity at 24 and 48 hours. To compare the activity within and between the different microbial strains, one-way analysis of variance (ANOVA) was used. To analyze the data, Statistical Package for the Social Sciences (SPSS) software version of 21.0 was used. The p-value ≤0.05 was considered as statistically significant. Results: Maximum inhibition zone was seen in both M. piperita extracts and 0.2% chlorhexidine with S. mutans at 24 and 48 hours, followed by A. actinomycetemcomitans, and C. albi-cans respectively. The statistical analysis ANOVA reveals the statistically significant association of M. piperita extracts with p-value <0.001. The comparison with 0.2% chlorhexidine at 24 hours showed a p-value of <0.04 and at 48 hours, it showed a p-value <0.001, which was statistically significant. Conclusion: The present study concluded that M. piperita showed antimicrobial activity against the oral microorganisms which are causing major less or more severe oral diseases and it can be administered as an alternative medicine for the conventional treatment. Clinical Significance: The study results serve as a guide in selecting and providing information about the efficacy of M. piperita extracts to the dental professionals. The discovery of a potential herbal medication would be a great development in the field of antimicrobial therapies.
Databáze:	MEDLINE
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