Efficacy and safety of noninvasive focused ultrasound for treatment of subcutaneous adiposity in healthy women.

Autor: Fonseca VM; a Dermatofunctional Aesthetics and Cosmetic Department , Ibramed Center for Education and Advanced Training (CEFAI) , Amparo , Brazil., Campos PS; a Dermatofunctional Aesthetics and Cosmetic Department , Ibramed Center for Education and Advanced Training (CEFAI) , Amparo , Brazil., Certo TF; a Dermatofunctional Aesthetics and Cosmetic Department , Ibramed Center for Education and Advanced Training (CEFAI) , Amparo , Brazil., de-Faria LT; a Dermatofunctional Aesthetics and Cosmetic Department , Ibramed Center for Education and Advanced Training (CEFAI) , Amparo , Brazil., Juliano PB; b Dermatofunctional Clinical Physiotherapist , Campinas , Brazil., Cintra DE; c Laboratory of Nutritional Genomics, School of Applied Sciences , University of Campinas (UNICAMP) , Campinas , Brazil., Liebano RE; d Physiotherapy Department , Federal University of São Carlos (UFSCar) , São Carlos-SP , Brazil., da Silva C; e Researchers at Research, Development & Innovation Department IBRAMED , Ibramed Research Group (IRG) , Amparo , Brazil.; f Clinical Laboratory, Ibramed Center for Education and Advanced Training (CEFAI) , Amparo , Brazil.; g Department of Physical Education, Institute of Biosciences , São Paulo State University (UNESP) , Rio Claro , Brazil., Guidi RM; e Researchers at Research, Development & Innovation Department IBRAMED , Ibramed Research Group (IRG) , Amparo , Brazil.; f Clinical Laboratory, Ibramed Center for Education and Advanced Training (CEFAI) , Amparo , Brazil.; h Biomedical Engineering Department, Faculty of Electrical Engineering and Computing , University of Campinas (UNICAMP) , Campinas , Brazil., Sant'Ana E; e Researchers at Research, Development & Innovation Department IBRAMED , Ibramed Research Group (IRG) , Amparo , Brazil.; f Clinical Laboratory, Ibramed Center for Education and Advanced Training (CEFAI) , Amparo , Brazil.
Jazyk: angličtina
Zdroj: Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology [J Cosmet Laser Ther] 2018 Oct; Vol. 20 (6), pp. 341-350. Date of Electronic Publication: 2018 Oct 04.
DOI: 10.1080/14764172.2018.1511907
Abstrakt: Introduction: In recent years, a new method focused ultrasound (FUS) has been used in the treatment of localized fat. The objectives of this work were to evaluate the efficacy and safety of the FUS in the treatment of abdominal subcutaneous fat.
Materials and Methods: Thirty-one healthy women were divided into two groups: G1 (N = 7), 6 sessions, 3 passes, once a week and G2 (N = 23), 10 sessions, 2 passes, twice a week. Outcome measures were reduction of circumference and fat thickness. Safety monitoring included laboratory testing (serum lipids profile and liver function tests) and adverse events were also assessed. Patient satisfaction and tolerance questionnaires were also applied. One patient underwent abdominoplasty and received a single session of FUS 24 h before surgery and a skin sample was collected for histological analysis.
Results: The results showed improvement in body contouring and reduction of the thickness of the fat layer observed by ultrasonography in both groups: G1 (P < 0.001) and G2 (P < 0.0001). The histology showed disrupted adipocytes and collapsed membranes 24 h after the FUS treatment.
Conclusion: FUS represents an effective and safe treatment for reducing localized adipose tissue by adipocytolysis.
Databáze: MEDLINE
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