A case of Histoplasma capsulatum variety capsulatum septic arthritis successfully treated with surgery, systemic antifungals, and local amphotericin cement beads.
| Autor: | Compton J; Department of Orthopedic Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA., Vander Voort W; Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Willey M; Department of Orthopedic Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA., Sekar P; Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA. Electronic address: poorani-sekar@uiowa.edu. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2018 Dec; Vol. 77, pp. 23-25. Date of Electronic Publication: 2018 Sep 28. |
| DOI: | 10.1016/j.ijid.2018.09.023 |
| Abstrakt: | Histoplasma capsulatum variety capsulatum (H. capsulatum) is a thermally dimorphic fungus that is endemic to the Mississippi River and Ohio River valley regions. Of the hundreds of thousands of patients exposed to this fungus, less than 1% develop a severe illness most commonly manifesting as pulmonary disease. Septic arthritis from hematogenous seeding with H. capsulatum or from direct inoculation has been reported only rarely in the literature. The first case of septic arthritis of the shoulder due to H. capsulatum occurring in an immunocompromised patient, treated successfully with irrigation and debridement, systemic antifungals, and local delivery of amphotericin B with cement beads, is reported here. Importantly, the addition of local amphotericin B delivery by cement beads to conventional treatment likely led to clinical cure in this patient. (Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|