Five-Year Antimicrobial Susceptibility of Pseudomonas aeruginosa from a Local Tertiary Hospital in Bacolod City, Philippines.

Autor:	Juayang AC; Clinical Laboratory, Dr. Pablo O. Torre Memorial Hospital, Bacolod City 6100, Philippines. alainjuayang@yahoo.com.; Medical Technology Program, Colegio San Agustin, Bacolod City 6100, Philippines. alainjuayang@yahoo.com., Lim JPT; Clinical Laboratory, Dr. Pablo O. Torre Memorial Hospital, Bacolod City 6100, Philippines. djozip@gmail.com., Bonifacio AFV; Medical Technology Program, Colegio San Agustin, Bacolod City 6100, Philippines. annefrancis301996@gmail.com., Lambot AVL; Medical Technology Program, Colegio San Agustin, Bacolod City 6100, Philippines. lalaicavictoria@yahoo.com., Millan SM; Medical Technology Program, Colegio San Agustin, Bacolod City 6100, Philippines. sean_maybelle@yahoo.com., Sevilla VZJN; Medical Technology Program, Colegio San Agustin, Bacolod City 6100, Philippines. maigeck@yahoo.com., Sy JKT; Medical Technology Program, Colegio San Agustin, Bacolod City 6100, Philippines. julienkatesy@gmail.com., Villanueva PJ; Medical Technology Program, Colegio San Agustin, Bacolod City 6100, Philippines. pauljohnvil95@gmail.com., Grajales CP; Medical Technology Program, Colegio San Agustin, Bacolod City 6100, Philippines. cadekid@yahoo.com., Gallega CT; Clinical Laboratory, Dr. Pablo O. Torre Memorial Hospital, Bacolod City 6100, Philippines. gallegachristine@yahoo.com.
Jazyk:	angličtina
Zdroj:	Tropical medicine and infectious disease [Trop Med Infect Dis] 2017 Jul 12; Vol. 2 (3). Date of Electronic Publication: 2017 Jul 12.
DOI:	10.3390/tropicalmed2030028
Abstrakt:	Over five years, a total of 646 P. aeruginosa isolates was acquired from different clinical specimens and their resistance to the commonly used anti-pseudomonal antibiotics was determined. The majority of the isolates were from respiratory (60.99%) and urinary sources (23.22%) while the least came from transudates and exudates (2.01%). Most of the samples were acquired from older adults (77.55%), most of whom were admitted (67.03%). Amikacin was found to be the most effective drug with a resistance rate of 7.5%, followed by piperacillin/tazobactam (8.5%) and gentamicin (13.5%). On the other hand, 26.7% of the isolates were resistant to levofloxacin. Almost 100% of the isolates were screened positive for AmpC production, which may suggest inducible resistance against expanded spectrum beta-lactamase. Furthermore, for the last three years, P. aeruginosa isolates from this area have been noted to have decreasing resistance only to aztreonam and gentamicin. Also, for five years, a mean MAR index of 0.17 was noted which indicates either proper antibiotic use or most isolates did not come from high-risk areas. Moreover, there was no significant difference in the resistance of P. aeruginosa when compared by specimen source ( p = 0.662), but significant when compared by year band ( p = 0.02). Competing Interests: The authors declare neither conflict nor competing interest exist.
Databáze:	MEDLINE
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