Pulmonary cysts in smoking-related interstitial fibrosis: a form of pseudocyst secondary to pulmonary interstitial emphysema.

Autor:	Marco VS; From the Department of Pathology, University General Hospital, Valencia, Spain. Electronic address: vicente.sabater@uv.es., Abad CS; From the Department of Pneumology, University General Hospital, Valencia, Spain., Fabrellas EF; From the Department of Pneumology, University General Hospital, Valencia, Spain., Samper GJ; From the Department of Pneumology, University General Hospital, Valencia, Spain; From the Departement of Medicine. Valencia University, Valencia, Spain.
Jazyk:	angličtina
Zdroj:	Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia [Rev Esp Patol] 2018 Oct - Dec; Vol. 51 (4), pp. 257-261. Date of Electronic Publication: 2018 Mar 14.
DOI:	10.1016/j.patol.2018.01.005
Abstrakt:	Smoking-related interstitial fibrosis is a distinct form of fibrosis, found in smokers, which has striking histopathological features. We present a case of pulmonary interstitial fibrosis with cysts in a 58-year-old woman who was a significant active smoker, presenting with a 7 month history of progressive dyspnea. TAC revealed thin-walled pulmonary cysts. An open lung biopsy was performed and the histopathological study showed hyaline fibrous thickening of the alveolar septa, respiratory bronchiolitis and cysts in the thickness of the interlobar septa. Immunohistochemically, the absence of an epithelial, vascular or lymphatic endothelial lining of the cysts would suggest that the cysts had been caused by pulmonary interstitial emphysema. Immunohistochemistry is essential in the differential diagnosis that includes, in this case, true cysts, pseudocysts and pulmonary lymphangiectasia. (Copyright © 2018 Sociedad Española de Anatomía Patológica. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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