Surveillance of Rabies Postexposure Prophylaxis in Greece: 4 Years Experience.

Autor: Dougas G; 1 Hellenic Center for Disease Control and Prevention, Athens, Greece., Konte V; 1 Hellenic Center for Disease Control and Prevention, Athens, Greece., Mitrou K; 1 Hellenic Center for Disease Control and Prevention, Athens, Greece., Georgakopoulou T; 1 Hellenic Center for Disease Control and Prevention, Athens, Greece., Baka A; 1 Hellenic Center for Disease Control and Prevention, Athens, Greece., Liona A; 1 Hellenic Center for Disease Control and Prevention, Athens, Greece., Tatsiou D; 1 Hellenic Center for Disease Control and Prevention, Athens, Greece., Metallidis S; 2 First Internal Medicine Department, Infectious Diseases Division, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Istikoglou I; 3 Infection Control Committee, 'AHEPA' University Hospital, Thessaloniki, Greece., Christodoulou E; 4 Department of Internal Medicine, 'G. Papanikolaou' General Hospital of Thessaloniki, Thessaloniki, Greece., Stavrakakis M; 4 Department of Internal Medicine, 'G. Papanikolaou' General Hospital of Thessaloniki, Thessaloniki, Greece., Pargiana C; 5 Infectious Diseases Hospital of Thessaloniki, Thessaloniki, Greece., Tsalikoglou F; 6 Ministry of Health, Athens, Greece., Tzani M; 7 Department of Zoonoses, Animal Health Directorate, Directorate General of Veterinary Services, Ministry of Rural Development and Food, Athens, Greece., Korou LM; 7 Department of Zoonoses, Animal Health Directorate, Directorate General of Veterinary Services, Ministry of Rural Development and Food, Athens, Greece., Tasioudi K; 8 Virology Laboratory - National Reference Laboratory for Rabies in Animals, Department of Molecular Diagnostics, FMD, Virological, Rickettsial & Exotic Diseases, Athens Veterinary Center, Ministry of Rural Development and Food, Athens, Greece., Mavrouli M; 9 Department of Microbiology, Medical School, University of Athens, Athens, Greece., Vrioni G; 9 Department of Microbiology, Medical School, University of Athens, Athens, Greece., Tsiodras S; 10 National and Kapodistrian University of Athens Medical School, Athens, Greece.
Jazyk: angličtina
Zdroj: Vector borne and zoonotic diseases (Larchmont, N.Y.) [Vector Borne Zoonotic Dis] 2019 Apr; Vol. 19 (4), pp. 295-301. Date of Electronic Publication: 2018 Sep 22.
DOI: 10.1089/vbz.2018.2344
Abstrakt: Rabies reemerged in Greek fauna during October 2012, 25 years after the last report in animals and 42 after the last human case. This study examined the administration of rabies postexposure prophylaxis (PEP) in humans over the period 2012-2016. A total of 1,454 individuals (62.6% males) received PEP. The vast majority (92.3%) of regimens was initiated in high risk for animal rabies areas (11.1 PEP per 100,000 residents per year). Among the exposed, 77.0% presented at a healthcare setting during the first 24 h after the incident; more severe injuries were associated with faster presentation (p < 0.05). A vaccine series was administered in 54.5% of exposed persons whereas 43.7% received both vaccine and immunoglobulin and 1.7% immunoglobulin only. Exposure to stray dogs represented 68.4% of all incidents. In exposures occurring in nonhigh risk for rabies areas, bat was the second most frequently involved animal (13.4% of incidents). All dogs and cats evaluated by a veterinarian and laboratory-confirmed rabid were initially deemed suspect for rabies during clinical examination or according to history. No human rabies cases were recorded during the period of the study. Surveillance of PEP represents a valuable tool for aiding assessment of present and future demands in prophylaxis biologicals, outlining the epidemiological profile of exposures and planning effective policies for the management of exposure incidents.
Databáze: MEDLINE
Externí odkaz: