Subacute sensory neuronopathy secondary to dorsal root ganglionitis in primary Sjögren's syndrome.

Autor: Malinow K, Yannakakis GD, Glusman SM, Edlow DW, Griffin J, Pestronk A, Powell DL, Ramsey-Goldman R, Eidelman BH, Medsger TA Jr, et. al.
Jazyk: angličtina
Zdroj: Annals of neurology [Ann Neurol] 1986 Oct; Vol. 20 (4), pp. 535-7.
DOI: 10.1002/ana.410200416
Abstrakt: Sensory neuropathies, particularly trigeminal neuropathy, have been recognized as neurological complications of Sjögren's syndrome, but the pathogenesis has not been established. We describe a woman with primary Sjögren's syndrome who developed a progressive debilitating subacute sensory neuronopathy. Results of electrophysiological studies were consistent with involvement of the trigeminal and dorsal root ganglia. A thoracic dorsal root ganglion biopsy showed lymphocytic infiltration and degeneration of ganglion cells. We believe that this is the first description of biopsy-documented dorsal root ganglionitis in a subacute sensory neuronopathy associated with Sjögren's syndrome and that the finding suggests an immunopathogenic basis.
Databáze: MEDLINE