Photodynamic action of erythrosin B as a toxic mechanism for infective larvae of bovine gastrointestinal nematodes.

Autor: Hawkins JA, Johnson-Delivorias MH, Heitz JR
Jazyk: angličtina
Zdroj: Veterinary parasitology [Vet Parasitol] 1986 Oct; Vol. 21 (4), pp. 265-70.
DOI: 10.1016/0304-4017(86)90052-x
Abstrakt: The effect of erythrosin B on adults and 3rd stage larvae of gastrointestinal nematodes of cattle was studied by treating calves per os with 20 mg kg-1, 40 mg kg-1, and 60 mg kg-1 of the dye daily for 21 days and monitoring its effect. Erythrosin B had no detectable effect on adult nematode fecundity or viability. Data collected did indicate, however, that erythrosin B produced a consistent toxic effect on 3rd stage larvae after exposure to fluorescent light. This toxic effect was dependent upon dosage of erythrosin B administered, time of light exposure and, to a much lesser extent, the length of time the larvae were left in culture in the presence of the dye.
Databáze: MEDLINE