Tumefactive multiple sclerosis masquerade as a central nervous system tumor: a case report.

Autor: Turkistani AN; College of Medicine, Imam Abdulrahman bin Faisal University, Khobar, Saudi Arabia., Alshamrani FJ; Assistant Professor, Consultant Neurologist, Department of Neurology, King Fahd Hospital of the University, Imam Abdulrahman bin Faisal University, Khobar, Saudi Arabia., Shareefi GF; College of Medicine, Imam Abdulrahman bin Faisal University, Khobar, Saudi Arabia., Alsulaiman A; Assistant Professor, Consultant Neurologist, Department of Neurology, King Fahd Hospital of the University, Imam Abdulrahman bin Faisal University, Khobar, Saudi Arabia.
Jazyk: angličtina
Zdroj: Electronic physician [Electron Physician] 2018 Aug 25; Vol. 10 (8), pp. 7180-7184. Date of Electronic Publication: 2018 Aug 25 (Print Publication: 2018).
DOI: 10.19082/7180
Abstrakt: Introduction: Tumefactive multiple sclerosis is a demyelinating disorder that appears tumor-like on MRI. To most physicians, diagnosing tumefactive MS by applying clinical, radiological, or laboratory examination like Cerebrospinal fluid (CSF) analysis, can be challenging and ultimately biopsy is necessary to confirm the diagnosis.
Case Presentation: This paper reports a case of a 37-year-old woman who presented with progressive headache and a strong family history of cancer and was misdiagnosed as having a CNS glioma. After considering the MRI features, CSF analysis results and observing improvement with IV steroids, the diagnosis of tumefactive MS was made. The patient refused biopsy to rule out the possibility of tumor or abscess. Nine months later, she presented with another relapse and an injectable disease modifying treatment (DMT) was initiated, and her course has been stable in follow up.
Take-Away Lesson: The overall clinical importance of this case report is to highlight the real possibility of being forced to decide between Tumefactive demyelinating lesions (TDLs) and brain tumors in clinical practice, in order to avoid unnecessary biopsy.
Competing Interests: Conflict of Interest: There is no conflict of interest to be declared.
Databáze: MEDLINE