Large artery stiffness according to different assessment methods in adult population of St.Petersburg.

Autor: Alieva AS; Almazov National Medical Research Centre, Saint Petersburg, Russia; Department of Pharmacological and Biomolecular Sciences (DisFeB), University of Milan, Milan, Italy. Electronic address: fmrc@almazovcentre.ru., Rotar OP; Almazov National Medical Research Centre, Saint Petersburg, Russia., Orlov AV; Almazov National Medical Research Centre, Saint Petersburg, Russia., Boyarinova MA; Almazov National Medical Research Centre, Saint Petersburg, Russia., Moguchaya EV; Almazov National Medical Research Centre, Saint Petersburg, Russia., Rogoza AN; National Medical Research Center of Cardiology, Moscow, Russia., Konradi AO; Almazov National Medical Research Centre, Saint Petersburg, Russia; ITMO University, Saint-Petersburg, Russia., Shlyakhto EV; Almazov National Medical Research Centre, Saint Petersburg, Russia.
Jazyk: angličtina
Zdroj: Atherosclerosis. Supplements [Atheroscler Suppl] 2018 Sep; Vol. 35, pp. e1-e5. Date of Electronic Publication: 2018 Aug 24.
DOI: 10.1016/j.atherosclerosissup.2018.08.001
Abstrakt: Objective: The aim of the present study was to assess the prevalence of increased arterial stiffness by different diagnostic methods and its association with cardiovascular risk in Russian population-based cohort.
Design and Methods: In terms of Russian epidemiological study ESSE-RF a random selection of 452 apparently healthy Saint-Petersburg inhabitants aged 25-65 years was performed. Fasting lipids, glucose and blood pressure measurements were performed. We used 3 diagnostic methods of arterial stiffness assessment: pulse wave velocity by applanation tonometry (SphygmoCor - PWV-S) and pulse wave velocity by volumetric sphygmography (VaSera - PWV-V), and cardio-ankle vascular index (CAVI) by VaSera.
Results: 341 (75,4%) had normal parameters of arterial stiffness assessed by all methods. Spearmen's coefficient of correlation and "kappa" coefficient for PWV-S and CAVI were 0,74 and 0,04, for PWV-S and PWV-V - 0,10 and 0,06, for CAVI and PWV-V - 0,28 and 0,03, respectively. There was a significant correlation between cardiovascular risk (defined by SCORE) and PWV-S (r = 0,38, p < 0,001) and a non-significant trend of increasing CAVI along with cardiovascular risk (r = 0,35, p = 0,14).
Conclusions: Different methods of arterial stiffness assessment showed a weak correlation with each other. Carotid-femoral pulse wave velocity detected by applanation tonometry is associated with high cardiovascular risk score and might be considered as better additional risk marker for cardiovascular risk stratification.
(Copyright © 2018. Published by Elsevier B.V.)
Databáze: MEDLINE
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