Quantitative approaches of nanofibers organization for biomedical patterned nanofibrous scaffold by image analysis.

Autor: Shah Hosseini N; Laboratoire de Physique et Mécanique Textiles EA 4365-UHA Mulhouse, Mulhouse, France., Simon B; Laboratoire de Modélisation Intelligence Processus Systèmes (MIPS) EA 2332-UHA Mulhouse, Mulhouse, France., Messaoud T; École nationale d'ingénierie, Université de Monastir, Monastir, Tunisia., Khenoussi N; Laboratoire de Physique et Mécanique Textiles EA 4365-UHA Mulhouse, Mulhouse, France., Schacher L; Laboratoire de Physique et Mécanique Textiles EA 4365-UHA Mulhouse, Mulhouse, France., Adolphe D; Laboratoire de Physique et Mécanique Textiles EA 4365-UHA Mulhouse, Mulhouse, France.
Jazyk: angličtina
Zdroj: Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2018 Nov; Vol. 106 (11), pp. 2963-2972. Date of Electronic Publication: 2018 Sep 08.
DOI: 10.1002/jbm.a.36485
Abstrakt: This study proposes a novel design of a laboratory built static collector using the 3D printing technology. This new collector produces aligned-to-random nanofibers in nanofibrous scaffold through electrospinning process. A design of experiment (DOE), based on response surface, analyzes the effect of the main process parameters; concentration, voltage, and distance; on the responses diameter and orientation. A quantifying approach has been used to investigate the orientation of nanofibers in the produced patterned scaffold through Fourier transforms method. The obtained results have proven a good potential to be used in tissue engineering application, especially for cells requiring specific guidance. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 2963-2972, 2018.
(© 2018 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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