[Complications of hyperthermic intraperitoneal chemotherapy: about a case of acute respiratory distress syndrome].

Autor: Mathy X; Service d'Anesthésie-Réanimation, CHU Sart Tilman, Liège, Belgique., Ancion A; Service de Cardiologie, CHU Sart Tilman, Liège, Belgique., Joris J; Service d'Anesthésie-Réanimation, CHU Sart Tilman, Liège, Belgique.
Jazyk: francouzština
Zdroj: Revue medicale de Liege [Rev Med Liege] 2018 Sep; Vol. 73 (9), pp. 442-446.
Abstrakt: For about twenty years, extensive cytoreduction surgery associated to hyperthermic intraperitoneal chemotherapy (HIPEC) has been used to treat rare peritoneal tumors (mesothelioma, pseudomyxoma) and some digestive and gynecological neoplasias infiltrating the peritoneum. This heavy technique is associated to significant morbi-mortality but allows to increase lifetime and to improve quality of life of patients with these tumours. Complications of this technique are principally surgical, but hyperthermic intraperitoneal chemotherapy can result in toxic effects, especially for kidney and bone marrow. Lung injury due to toxicity of chemotherapeutic agents, sometimes serious and potentially leading to acute distress respiratory syndrome (ARDS) has already been described in the postoperative period of HIPEC, but never intraoperatively. We report the case of an ARDS developing intraoperatively during an extensive cytoreduction surgery associated to HIPEC, due to the toxicity of the chemotherapeutic agents.
Databáze: MEDLINE