Enhancing mechanical properties of an injectable two-solution acrylic bone cement using a difunctional crosslinker.

Autor: Wiegand MJ; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York, 13244.; Syracuse Biomaterials Institute, Syracuse University, Syracuse, New York, 13244., Faraci KL; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York, 13244.; Syracuse Biomaterials Institute, Syracuse University, Syracuse, New York, 13244., Reed BE; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York, 13244.; Syracuse Biomaterials Institute, Syracuse University, Syracuse, New York, 13244., Hasenwinkel JM; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York, 13244.; Syracuse Biomaterials Institute, Syracuse University, Syracuse, New York, 13244.
Jazyk: angličtina
Zdroj: Journal of biomedical materials research. Part B, Applied biomaterials [J Biomed Mater Res B Appl Biomater] 2019 Apr; Vol. 107 (3), pp. 783-790. Date of Electronic Publication: 2018 Sep 05.
DOI: 10.1002/jbm.b.34172
Abstrakt: Two-solution bone cements modified with ethylene glycol-dimethacrylate (EG-DMA) as a crosslinker have been developed as an attempt to further improve the mechanical properties of acrylic bone cement. The result of this study shows that EG-DMA can increase the mechanical properties and fractional monomer conversion while preserving the thermal characteristics. The strength and bending modulus increase with EG-DMA concentrations at 5-10 vol % EG-DMA. Substituting the EG-DMA content past 10 vol % decreases the bending properties due to the effects of reduced monomer concentrations. Strengthened EG-DMA samples demonstrated an increase in ductility with noticeably different fracture surface morphologies than the control samples, indicated by microtroughs and ridge formation caused by excessive plastic strain. This work provides insight into the effect of substituting a crosslinker for MMA monomer in an injectable two-solution system and lays out the ideal concentrations of EG-DMA for superior mechanical or fractional monomer conversion properties. © 2018 Wiley Periodicals, Inc. J. Biomed. Mater. Res. Part B, 2018. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 107B: 783-790, 2019.
(© 2018 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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