| Autor: |
Gorustovich AA; Interdisciplinary Materials Group-IESIING-UCASAL, INTECIN UBA-CONICET, A4400EDD, Salta, Argentina. agorustovich@conicet.gov.ar., Nielsen FH; Research Nutritionist Consultant, Grand Forks, ND, USA. |
| Jazyk: |
angličtina |
| Zdroj: |
Biological trace element research [Biol Trace Elem Res] 2019 Mar; Vol. 188 (1), pp. 221-229. Date of Electronic Publication: 2018 Sep 04. |
| DOI: |
10.1007/s12011-018-1499-3 |
| Abstrakt: |
Scientific evidence has shown the nutritional importance of boron (B) in the remodeling and repair of cancellous bone tissue. However, the effects of the nutritional deficiency of B on the cortical bone tissue of the appendicular skeleton have not yet been described. Thus, a study was performed to histomorphometrically evaluate the density of osteocyte lacunae of cortical bone of mouse femora under conditions of nutritional deficiency of B and to analyze the effects of the deficiency on the biomechanical properties of mouse tibiae. Weaning, 21-day-old male Swiss mice were assigned to the following two groups: controls (B+; n = 10) and experimental (B-; n = 10). Control mice were fed a basal diet containing 3 mg B/kg, whereas experimental mice were fed a B-deficient diet containing 0.07 mg B/kg for 9 weeks. The histological and histomorphometric evaluations of the mice fed a B-deficient diet showed a decrease in the density of osteocyte lacunae in the femoral cortical bone tissue and the evaluation of biomechanical properties showed lower bone rigidity in the tibia. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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