Impact of exercise intensity on oxidative stress and selected metabolic markers in young adults in Ghana.

Autor: Diaba-Nuhoho P; Division of Vascular Endothelium and Microcirculation, Department of Medicine III, University of Technology Dresden, Fetscherstr. 74, 01307, Dresden, Germany. Patrick.Diaba-Nuhoho@uniklinikum-dresden.de., Ofori EK; Department of Physiology, University of Lausanne, Lausanne, Switzerland., Asare-Anane H; Department of Chemical Pathology, University of Ghana, Korle-Bu, Accra, Ghana., Oppong SY; Department of Chemical Pathology, University of Ghana, Korle-Bu, Accra, Ghana., Boamah I; Department of Microbiology, University of Ghana School of Medicine and Dentistry, Korle-Bu, Accra, Ghana., Blackhurst D; Division of Chemical Pathology, University of Cape Town, Observatory, Cape Town, 7925, South Africa.
Jazyk: angličtina
Zdroj: BMC research notes [BMC Res Notes] 2018 Sep 03; Vol. 11 (1), pp. 634. Date of Electronic Publication: 2018 Sep 03.
DOI: 10.1186/s13104-018-3758-y
Abstrakt: Objective: This study aimed to evaluate the effect of different levels of exercise on markers of oxidative stress and selected metabolic parameters in Ghanaian young adults.
Results: Significant increases in a marker of oxidative stress malondialdehyde and antioxidants such as superoxide dismutase and uric acid were observed in the exercisers compared with the inactive group (p < 0.05). Total cholesterol and high density lipoprotein levels were significantly different (p < 0.05) between the two groups. Positive associations between exercise intensity, antioxidant concentration and malondialdehyde were observed within the exercise group for vigorous exercise with regards to uric acid, superoxide dismutase and malondialdehyde (r = 0.512, p = 0.004; r = 0.810, p = 0.001; r = 0.715, p = 0.001) respectively and moderate exercise vs malondialdehyde (r = 0.841, p = 0.001) compared to the inactive group. Exercise participants performed more vigorous exercise (p < 0.001), moderate exercise (p < 0.001) and more walking (p < 0.001) compared with the inactive group while the inactive group exhibited more sitting (p < 0.001). The study provides a first report on the risk associated with increase in oxidative stress and the importance of walking as a health promotion intervention among young Ghanaian adults.
Databáze: MEDLINE
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