[Non-allergic rhinitis with eosinophilic syndrome. Case report].
| Autor: | Collado-Chagoya R; Secretaría de Salud, Hospital General de México, Servicio de Inmunología Clínica y Alergia, Ciudad de México, México. rodnova87@hotmail.com., Hernández-Romero J, Eliosa-Alvarado GA, García-González AC, Campos-Gutiérrez RI, Velasco-Medina AA, Velázquez-Sámano G |
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| Jazyk: | Spanish; Castilian |
| Zdroj: | Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) [Rev Alerg Mex] 2018 Jul-Sep; Vol. 65 (3), pp. 310-315. |
| DOI: | 10.29262/ram.v65i3.336 |
| Abstrakt: | Background: Rhinitis is the leading cause for consultation in the allergy department. It consists in chronic inflammation of the nasal mucosa. Non-allergic rhinitis with eosinophilic syndrome is characterized by chronic inflammation of the nasal mucosa (> 20% of eosinophils in nasal cytology) in the absence of demonstrable allergy (negative in vivo and in vitro tests); often it is accompanied by other sinonasal conditions (nasal polyposis, chronic rhinosinusitis), and it constitutes a risk factor for the development of obstructive sleep apnea. Case Report: Seven-year old girl with rhinorrhea, nasal obstruction, nasopalatine itching, and severe sneezing that limited sleep and school activities. This condition had a seasonal pattern, with important blood (800 eosinophils/μL) and nasal (30%) eosinophilia and absence of demonstrable allergy (negative skin tests, negative specific nasal challenge tests); the non-allergic rhinitis with eosinophilic syndrome diagnosis was verified. Conclusions: Non-allergic rhinitis with eosinophilic syndrome is considered to be a highly underdiagnosed disease owing to the lack of in vivo nasal tests' performance; to this underestimation, incorrect nasal etiology and lack of local in vivo tests (nasal specific IgE) are added, which warrants a high degree of diagnostic suspicion by the specialist physician. |
| Databáze: | MEDLINE |
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