Clinical Evaluation of an Individualized Risk Prediction Tool for Men on Active Surveillance for Prostate Cancer.

Autor: Huntley JH; Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD., Coley RY; Kaiser Permanente Washington Health Research Institute, Seattle, WA., Carter HB; Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD., Radhakrishnan A; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI., Krakow M; National Cancer Institute, National Institutes of Health, Bethesda, MD., Pollack CE; Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD. Electronic address: cpollac2@jhmi.edu.
Jazyk: angličtina
Zdroj: Urology [Urology] 2018 Nov; Vol. 121, pp. 118-124. Date of Electronic Publication: 2018 Aug 30.
DOI: 10.1016/j.urology.2018.08.021
Abstrakt: Objective: To determine whether providing individualized predictions of health outcomes to men on active surveillance (AS) alleviates cancer-related anxiety and improves risk understanding.
Materials and Methods: We consecutively recruited men from our large, institutional AS program before (n = 36) and after (n = 31) implementation of a risk prediction tool. Men in both groups were surveyed before and after their regular visits to assess their perceived cancer control, biopsy-specific anxiety, and burden from cancer-related information. We compared pre-/post-visit differences between men who were and were not shown the tool using two-sample t-tests. Satisfaction with and understanding of the predictions were elicited from men in the intervention period.
Results: Men reported a relatively high level of cancer control at baseline. Men who were not shown the tool saw a 6.3 point increase (scaled from 0 to 100) in their perceived cancer control from before to after their visit whereas men who were shown the tool saw a 12.8 point increase, indicating a statistically significant difference between groups (p = .04). Biopsy-specific anxiety and burden from cancer information were not significantly different between groups. Men were satisfied with the tool and demonstrated moderate understanding.
Conclusion: Providing individualized predictions to men on AS helps them better understand their cancer risk and should be considered at other clinical sites.
(Copyright © 2018. Published by Elsevier Inc.)
Databáze: MEDLINE
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