Basal cell carcinoma treated with Mohs micrographic surgery in young Ibero-American patients.

Autor: Aluma-Tenorio MS; Aurora, Centro Especializado en Cáncer de Piel, Medellín, Colombia., Ávila-Álvarez A; Universidad Pontificia Bolivariana, Medellín, Colombia., Jaimes N; Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Caballero-Uribe N; Aurora, Centro Especializado en Cáncer de Piel, Medellín, Colombia.; Universidade do federal do ABC, Santo André, SP, Brazil., González A; Instituto Médico Especializado Alexander Fleming, Buenos Aires, Argentina.; Instituto de Oncologia, Ángel H. Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina., Terzian LR; Universidade do federal do ABC, Santo André, SP, Brazil., Ocampo-Candiani J; Facultad de Medicina. Servicio de Dermatología, Universidad Autónoma de Nuevo León. Hospital Universitario, Monterrey, México., Zuluaga MA; Facultad de Medicina. Servicio de Dermatología, Universidad Autónoma de Nuevo León. Hospital Universitario, Monterrey, México., Garza-Rodríguez V; Facultad de Medicina. Servicio de Dermatología, Universidad Autónoma de Nuevo León. Hospital Universitario, Monterrey, México., Tamayo-Betancur MC; Aurora, Centro Especializado en Cáncer de Piel, Medellín, Colombia., Cuesta-Castro DP; Universidad Pontificia Bolivariana, Medellín, Colombia., Garcés JR; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.; Centro Médico Teknon, Barcelona, Catalunya, Spain., Ruiz-Salas V; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.; Centro Médico Teknon, Barcelona, Catalunya, Spain., Goldberg L; DermSurgery Associates, Houston, TX, USA., Kimyai-Asadi A; DermSurgery Associates, Houston, TX, USA.
Jazyk: angličtina
Zdroj: International journal of dermatology [Int J Dermatol] 2018 Dec; Vol. 57 (12), pp. 1447-1453. Date of Electronic Publication: 2018 Aug 31.
DOI: 10.1111/ijd.14195
Abstrakt: Background: The incidence of basal cell carcinoma (BCC) in younger individuals has increased in recent decades. However, the characteristics of BCCs in this population, especially in Ibero-Latin American countries, have not been completely defined.
Objective: To describe the demographic, clinical, and histopathological characteristics of BCCs in patients younger than 40 treated with Mohs Micrographic Surgery (MMS).
Materials and Methods: A multicenter, retrospective study conducted between January 2009 and December 2014, in five Ibero-American countries, included biopsy-proven BCCs in patients younger than 40 that were treated with MMS. Demographic, clinical, histopathological, and surgical characteristics were described.
Results: The study included 301 tumors in 241 patients, of whom 61% were female. The most common Fitzpatrick phototype was III. The most common histological subtypes were nodular (37.5%) and infiltrative (18.9%). Perineural invasion was encountered in 1.7%, and tumor clearance was achieved in 87.4% within two stages of MMS.
Conclusions: This is the first Ibero-Latin American transnational study describing the characteristics of BCCs in young patients treated with MMS. Despite darker skin phototypes in this population, BCCs can occur in early ages and may present with aggressive features. Therefore, MMS may be considered an appropriate first-line treatment option in this population.
(© 2018 The International Society of Dermatology.)
Databáze: MEDLINE
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