Lupus panniculitis: Clinicopathological features of a series of 12 patients.

Autor:	González-Cruz C; Servicio de Dermatología, Hospital Universitari Vall d'Hebron, Barcelona, España. Electronic address: carlos.gonzalez.cruz@hotmail.com., Aparicio Español G; Servicio de Dermatología, Hospital Universitari Vall d'Hebron, Barcelona, España., Ferrer Fàbrega B; Servicio de Anatomía Patológica, Hospital Universitari Vall d'Hebron, Barcelona, España., Cabezas Calderón V; Servicio de Dermatología, Hospital Universitari Vall d'Hebron, Barcelona, España., Giner Pichel M; Servicio de Anatomía Patológica, Hospital Universitari Vall d'Hebron, Barcelona, España., García-Patos Briones V; Servicio de Dermatología, Hospital Universitari Vall d'Hebron, Barcelona, España.
Jazyk:	English; Spanish; Castilian
Zdroj:	Medicina clinica [Med Clin (Barc)] 2018 Dec 14; Vol. 151 (11), pp. 444-449. Date of Electronic Publication: 2018 Aug 25.
DOI:	10.1016/j.medcli.2018.06.024
Abstrakt:	Background and Objective: Lupus panniculitis (LP) is a rare variant of chronic cutaneous lupus erythematosus, which diagnosis requires clinicopathological correlation, especially in those patients without any other manifestation of lupus erythematosus (LE). According to the phase when the biopsy is performed, histological findings can be non-specific. Few series have been published to date. Hence, we report our own experience in the diagnosis and management of this disease. Materials and Methods: We conducted a retrospective descriptive clinicopathological study of 12 patients diagnosed in our centre. Results: All the patients had painful and recurrent plaques and/or nodules, with a predilection for proximal extremities, face and scalp. Histopathologic examination showed mostly lobular panniculitis and lymphoplasmacytic infiltrate. For the diagnosis, we also considered the coexistence of other clinical manifestations of LE as well as the expression of CD123 by immunohistochemistry. In 3 patients, LP was the first manifestation of LE. Conclusions: The diagnosis of LP can be difficult. The presence of other clinical and/or histological manifestations of LE along with immunohistochemistry techniques could help in the differential diagnosis with other panniculitis. (Copyright © 2018 Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu