| Autor: |
Cobb MH, Burr JG, Linder ME, Gray TB, Gregory JS |
| Jazyk: |
angličtina |
| Zdroj: |
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1986 Jun 13; Vol. 137 (2), pp. 702-8. |
| DOI: |
10.1016/0006-291x(86)91135-6 |
| Abstrakt: |
Insulin and transformation by Rous sarcoma virus stimulate the phosphorylation of ribosomal protein S6. Soluble fractions containing activated S6 protein kinase from insulin-treated cells and from transformed chick embryo fibroblasts were compared. Based upon several characteristics notably elution from DEAE-cellulose and sedimentation in glycerol gradients, these two S6 protein kinase activities appear to be similar enzymes. Thus insulin and retroviral transformation may activate the same enzyme to regulate the phosphorylation state of S6. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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