Effects of consuming a high-protein diet with or without soy protein during weight loss and maintenance: a non-inferiority, randomized clinical efficacy trial.

Autor: Speaker KJ; Anschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA., Sayer RD; Anschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA., Peters JC; Anschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA., Foley HN; Anschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA., Pan Z; Department of Biostatistics and Informatics, Colorado School of Public Health University of Colorado Anschutz Medical Campus Aurora CO USA., Wyatt HR; Anschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA., Flock MR; Clinical & Translational Science Institute University of Pittsburgh Pittsburgh PA USA., Mukherjea R; Global Nutrition Innovation DuPont Nutrition & Health St. Louis MO USA., Hill JO; Anschutz Health and Wellness Center University of Colorado Anschutz Medical Campus Aurora CO USA.
Jazyk: angličtina
Zdroj: Obesity science & practice [Obes Sci Pract] 2018 May 21; Vol. 4 (4), pp. 357-366. Date of Electronic Publication: 2018 May 21 (Print Publication: 2018).
DOI: 10.1002/osp4.278
Abstrakt: Objective: This 12-month randomized, non-inferiority clinical trial sought to determine the impact of consuming soy protein as part of an energy-restricted, high-protein diet on weight loss, body composition and cardiometabolic health.
Methods: Seventy-one adults (58 female) with overweight or obesity (body mass index: 32.9 ± 3.6 kg m -2 ) were randomly assigned to consume three servings of soy (S) or non-soy (NS) protein foods per day for 12 months. All participants completed a group-based behavioural weight loss program lasting 4 months (M4), and follow-up assessments were completed at month 12 (M12).
Results: Body weight was reduced in both groups at M4 (S: -7.0% ± 5.2%, NS: -7.1% ± 5.7%) and M12 (S: 3.6% ± 5.1%, NS: -4.8% ± 7.3%). Body weight reductions (mean difference [90% confidence interval]) were not different between S and NS at either time point (M4: -0.16% [-1.4, 3.6], P  = 0.90; M12: 1.1% [-1.4, 3.6], P  = 0.44). Differences in body fat mass loss were not different between S and NS at M4 (0.29 ± 0.84 kg, P  = 0.73) or M12 (0.78 ± 1.5 kg, P  = 0.59). Weight loss-induced improvements in cholesterol, triglycerides and blood pressure did not differ between S and NS.
Conclusion: These results indicate that soy-based protein foods can be effectively incorporated into an energy-restricted, high-protein diet for improving body weight, body composition and cardiometabolic health.
Databáze: MEDLINE
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