[Up to date of pathophysiology mechanism of idiopathic nephrotic syndromes: Minimal change disease and focal and segmental glomerulosclerosis].

Autor: Dumas De La Roque C; Service de néphrologie transplantation et dialyse, centre hospitalier universitaire de Bordeaux, 33076 Bordeaux, France. Electronic address: charlotte.mannat@hotmail.fr., Combe C; Service de néphrologie transplantation et dialyse, centre hospitalier universitaire de Bordeaux, 33076 Bordeaux, France; Inserm U1026, université de Bordeaux, 33076 Bordeaux, France., Rigothier C; Service de néphrologie transplantation et dialyse, centre hospitalier universitaire de Bordeaux, 33076 Bordeaux, France; Inserm U1026, université de Bordeaux, 33076 Bordeaux, France.
Jazyk: francouzština
Zdroj: Nephrologie & therapeutique [Nephrol Ther] 2018 Dec; Vol. 14 (7), pp. 501-506. Date of Electronic Publication: 2018 Aug 24.
DOI: 10.1016/j.nephro.2018.06.001
Abstrakt: Idiopathic nephrotic syndrome represents up to 30% of adult glomerulopathies. However, its prognosis according to remission, relapse and renal failure remains unchanged since the 80s and prediction remains difficult. Physiopathology of adult idiopathic nephrotic syndrome is complex and multifactorial, including immunologic and environmental factors and a putative permeability-circulating factor, still unknown. In this point of view, we propose to summarize actual knowledge about idiopathic minimal change disease and focal and segmental glomerulosclerosis physiopathology.
(Copyright © 2018 Association Société de néphrologie. Published by Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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