Renal transplants from older deceased donors: Is pre-implantation biopsy useful? A monocentric observational clinical study.
Autor: | Colussi G; Fabio Rosario Salereno, Division of Nephrology, Dialysis and Renal Transplantatation, ASST Grande Ospedale Territoriale Niguarda, Milan 20162, Italy. giacomo.colussi@ospedaleniguarda.it., Casati C; Fabio Rosario Salereno, Division of Nephrology, Dialysis and Renal Transplantatation, ASST Grande Ospedale Territoriale Niguarda, Milan 20162, Italy., Colombo VG; Fabio Rosario Salereno, Division of Nephrology, Dialysis and Renal Transplantatation, ASST Grande Ospedale Territoriale Niguarda, Milan 20162, Italy., Camozzi MLP; Division of Pathology, ASST Grande Ospedale Territoriale Niguarda, Milan 20162, Italy., Salerno FR; School of Nephrology, Milano-Bicocca University, Milan 20126, Italy. |
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Jazyk: | angličtina |
Zdroj: | World journal of transplantation [World J Transplant] 2018 Aug 09; Vol. 8 (4), pp. 110-121. |
DOI: | 10.5500/wjt.v8.i4.110 |
Abstrakt: | Aim: To compare survival of kidney transplants from deceased extended criteria donors (ECD) according to: (1) donor graft histological score; and (2) allocation of high score grafts either to single (SKT) or dual (DKT) transplant. Methods: Renal biopsy was performed as part of either a newly adopted DKT protocol, or of surveillance protocol in the past. A total 185 ECD graft recipients were categorized according to pre-implantation graft biopsy into 3 groups: SKT with graft score 1 to 4 [SKT Results: There were no statistically significant differences in graft and patient survival between SKT Conclusion: In transplants from clinically suitable ECD donors, graft survival was similar irrespective of pre-implantation biopsy score and of allocation to SKT or DKT. These results suggest use of caution in the use of histology as the only decision criteria for ECD organ allocation. Competing Interests: Conflict-of-interest statement: The authors declare that they have no conflict of interest. |
Databáze: | MEDLINE |
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