Experience Reduces Surgical and Hardware-Related Complications of Deep Brain Stimulation Surgery: A Single-Center Study of 181 Patients Operated in Six Years.

Autor: Sorar M; Department of Neurosurgery, Diskapi Yildirim Beyazit Training and Research Hospital, Health Sciences University, Ankara, Turkey., Hanalioglu S; Department of Neurosurgery, Diskapi Yildirim Beyazit Training and Research Hospital, Health Sciences University, Ankara, Turkey., Kocer B; Department of Neurology, Diskapi Yildirim Beyazit Training and Research Hospital, Health Sciences University, Ankara, Turkey., Eser MT; Department of Neurosurgery, Diskapi Yildirim Beyazit Training and Research Hospital, Health Sciences University, Ankara, Turkey., Comoglu SS; Department of Neurology, Diskapi Yildirim Beyazit Training and Research Hospital, Health Sciences University, Ankara, Turkey., Kertmen H; Department of Neurosurgery, Diskapi Yildirim Beyazit Training and Research Hospital, Health Sciences University, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Parkinson's disease [Parkinsons Dis] 2018 Jul 22; Vol. 2018, pp. 3056018. Date of Electronic Publication: 2018 Jul 22 (Print Publication: 2018).
DOI: 10.1155/2018/3056018
Abstrakt: Objective: Deep brain stimulation (DBS) surgery has increasingly been performed for the treatment of movement disorders and is associated with a wide array of complications. We aimed to present our experience and discuss strategies to minimize adverse events in light of this contemporary series and others in the literature.
Methods: A retrospective chart review was conducted to collect data on age, sex, indication, operation date, surgical technique, and perioperative and late complications.
Results: A total of 181 patients (113 males, 68 females) underwent DBS implantation surgery (359 leads) in the past six years. Indications and targets were as follows: Parkinson's disease (STN) ( n =159), dystonia (GPi) ( n =13), and essential tremor (Vim) ( n =9). Mean age was 55.2 ± 11.7 (range 9-74) years. Mean follow-up duration was 3.4 ± 1.6 years. No mortality or permanent morbidity was observed. Major perioperative complications were confusion (6.6%), intracerebral hemorrhage (2.2%), stroke (1.1%), and seizures (1.1%). Long-term adverse events included wound (7.2%), mostly infection, and hardware-related (5.5%) complications. Among several factors, only surgical experience was found to be related with overall complication rates (early period: 31% versus late period: 10%; p =0.001).
Conclusion: The rates of both early and late complications of DBS surgery are acceptably low and decrease significantly with cumulative experience.
Databáze: MEDLINE
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