The antibacterial and physiological effects of pure and nanoencapsulated Origanum majorana essential oil on fish infected with Aeromonas hydrophila.

Autor: da Cunha JA; Universidade Federal de Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil., de Ávila Scheeren C; UFSM, Santa Maria, RS, Brazil., Fausto VP; Universidade Franciscana, Santa Maria, RS, Brazil., de Melo LDW; Center for Analysis and Research Organic, UFSM, Santa Maria, RS, Brazil., Henneman B; Center for Analysis and Research Organic, UFSM, Santa Maria, RS, Brazil., Frizzo CP; Center for Analysis and Research Organic, UFSM, Santa Maria, RS, Brazil., de Almeida Vaucher R; Center for Chemical, Pharmaceutical and Food Science, Universidade Federal de Pelotas, Pelotas, RS, Brazil., Castagna de Vargas A; Department of Preventive Veterinary Medicine, UFSM, Santa Maria, RS, Brazil., Baldisserotto B; Universidade Federal de Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil; Department of Physiology and Pharmacology, UFSM, 97105-900 Santa Maria, RS, Brazil. Electronic address: bernardo@smail.ufsm.br.
Jazyk: angličtina
Zdroj: Microbial pathogenesis [Microb Pathog] 2018 Nov; Vol. 124, pp. 116-121. Date of Electronic Publication: 2018 Aug 20.
DOI: 10.1016/j.micpath.2018.08.040
Abstrakt: This study evaluated the antibacterial activity of Origanum majorana essential oil (EOM) and nanocapsules of this oil (NOM) in silver catfish, Rhamdia quelen, infected with Aeromonas hydrophila, and addressed their effects on silver catfish hematological and metabolic parameters. Fish were inoculated with A. hydrophila (360 μL, at a concentration of 1.5 × 10 9  CFU mL -1 ) and submitted to 1 h daily baths with EOM (0 (control), 20 or 30 μL L -1 ), NOM (0 (control), 5 or 10 μL L -1 ) or a positive control containing florfenicol (30 μL L -1 ) called group Maxflor ® for five consecutive days. All treatments improved the survival rate of the infected fish, but we suggest the treatment of A. hydrophila infections through daily baths with 20 μL L -1 EOM or 5 μL L -1 NOM for five consecutive days as these were the lowest effective concentrations tested. Silver catfish treated with EOM and NOM had higher lymphocyte levels, indicating stimulation of the immune system in these fish. The lowest liver glucose level was found in the group treated with the lowest concentration of NOM, and the lactate values in the liver and muscle of all groups were within the normal values reported for this species. In addition, nanocapsules required much less EOM to elicit effective antibacterial treatment.
(Copyright © 2018. Published by Elsevier Ltd.)
Databáze: MEDLINE
Externí odkaz: