Childhood cancer research in Oxford II: The Childhood Cancer Research Group.

Autor: Draper GJ; Department of Statistics, University of Oxford, 24-29 St Giles, Oxford, OX1 3LB, UK. gerald.draper@stats.ox.ac.uk., Bithell JF; Department of Statistics, University of Oxford, 24-29 St Giles, Oxford, OX1 3LB, UK., Bunch KJ; National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Old Road Campus, Oxford, OX3 7LF, UK., Kendall GM; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Old Road Campus, Oxford, OX3 7LF, UK., Murphy MFG; Nuffield Department of Women's and Reproductive Health, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Stiller CA; National Cancer Registration and Analysis Service, Public Health England, Chancellor Court, Oxford Business Park South, Oxford, OX4 2GX, UK.
Jazyk: angličtina
Zdroj: British journal of cancer [Br J Cancer] 2018 Sep; Vol. 119 (6), pp. 763-770. Date of Electronic Publication: 2018 Aug 21.
DOI: 10.1038/s41416-018-0181-z
Abstrakt: Background: We summarise the work of the Childhood Cancer Research Group, particularly in relation to the UK National Registry of Childhood Tumours (NRCT).
Methods: The Group was responsible for setting up and maintaining the NRCT. This registry was based on notifications from regional cancer registries, specialist children's tumour registries, paediatric oncologists and clinical trials organisers. For a large sample of cases, data on controls matched by date and place of birth were also collected.
Results: Significant achievements of the Group include: studies of aetiology and of genetic epidemiology; proposals for, and participation in, international comparative studies of these diseases and on a classification system specifically for childhood cancer; the initial development of, and major contributions to, follow-up studies of the health of long-term survivors; the enhancement of cancer registration records by the addition of clinical data and of birth records. The Group made substantial contributions to the UK government's Committee on Medical Aspects of Radiation in the Environment.
Conclusion: An important part of the ethos of the Group was to work in collaboration with many other organisations and individuals, both nationally and internationally: many of the Group's achievements described here were the result of such collaborations.
Databáze: MEDLINE
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