NO x in exhaled breath condensate is related to allergic sensitization in young and middle-aged adults.
Autor: | Aldakheel FM; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia., Bourke JE; Department of Pharmacology, Biomedicine Discovery Institute, Monash University, Melbourne, Vic., Australia., Thomas PS; Department of Respiratory Medicine & Prince of Wales Hospital Clinical School, University of New South Wales, Kensington, NSW, Australia., Matheson MC; Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.; Murdoch Children's Research Institute, Melbourne, Vic., Australia., Abramson MJ; School of Public Health & Preventive Medicine, Monash University, Melbourne, Vic., Australia., Hamilton GS; School of Clinical Sciences, Monash University, Melbourne, Vic., Australia.; Monash Lung and Sleep, Monash Health, Melbourne, Vic., Australia., Lodge CJ; Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.; Murdoch Children's Research Institute, Melbourne, Vic., Australia., Thompson BR; Allergy, Immunology and Respiratory Medicine, the Alfred Hospital, Melbourne, Vic., Australia.; Central Clinical School, Monash University, Melbourne, Vic., Australia., Walters EH; School of Medicine, University of Tasmania, Hobart, TAS, Australia., Allen KJ; Murdoch Children's Research Institute, Melbourne, Vic., Australia., Erbas B; School of Public Health, La Trobe University, Melbourne, Vic., Australia., Perret JL; Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.; Centre for Air quality and health Research and evaluation (CAR), Melbourne, Vic., Australia., Dharmage SC; Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.; Murdoch Children's Research Institute, Melbourne, Vic., Australia., Lowe AJ; Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.; Murdoch Children's Research Institute, Melbourne, Vic., Australia. |
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Jazyk: | angličtina |
Zdroj: | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2019 Feb; Vol. 49 (2), pp. 171-179. Date of Electronic Publication: 2018 Sep 07. |
DOI: | 10.1111/cea.13251 |
Abstrakt: | Background: Asthma and allergic diseases are heterogeneous. Measurement of biomarkers in exhaled breath condensate (EBC) may help to discriminate between different phenotypes and may assist with clinical prognostication. Objectives: We aimed to assess associations between total nitric oxide products (NO Methods: Cross-sectional analyses were nested within two Australian longitudinal studies, the Melbourne Atopy Cohort Study (MACS, mean age 17.8 years) and the Tasmanian Longitudinal Health Study (TAHS, mean age 49.4 years). Levels of EBC NO Results: Atopy, with or without asthma or rhinitis, was associated with increased EBC NO Conclusions and Clinical Relevance: In these population-based samples, EBC NO (© 2018 John Wiley & Sons Ltd.) |
Databáze: | MEDLINE |
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