Assessment of Photodynamic Therapy and Nanoparticles Effects on Caries Models.

Autor: Saafan A; Dental Laser Applications Department, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Cairo, Egypt., Zaazou MH; Restorative and Dental Materials Department, Oral and Dental Research Division, National Research Centre, Cairo, Egypt., Sallam MK; Medical Microbiology and Immunology, Kasr El Aini Faculty of Medicine, Cairo University, Cairo, Egypt., Mosallam O; Restorative and Dental Materials Department, Oral and Dental Research Division, National Research Centre, Cairo, Egypt., El Danaf HA; Restorative and Dental Materials Department, Oral and Dental Research Division, National Research Centre, Cairo, Egypt.
Jazyk: angličtina
Zdroj: Open access Macedonian journal of medical sciences [Open Access Maced J Med Sci] 2018 Jul 12; Vol. 6 (7), pp. 1289-1295. Date of Electronic Publication: 2018 Jul 12 (Print Publication: 2018).
DOI: 10.3889/oamjms.2018.241
Abstrakt: Aim: To assess the antibacterial competence of 650 nm diode laser, Methylene Blue (MB) and Silver Nano-Particles (Ag NPs) on Streptococcus mutans in biofilm-induced caries models.
Material and Methods: One hundred eighty specimens were prepared and equally divided into 6 groups. One group was untreated (control), and the others were subjected to either MB, laser, Ag NPs, the combination of MB and Laser or MB, laser and Ag NPs.
Results: Comparison of the log10 mean Colony Forming Units per millilitre (CFU/ml) values of each of the treated 5 groups and the control group was found statistically significant (P-value < 0.05). The combination of MB, laser and Ag NPs recorded the greatest reduction (95.28%). MB alone represented the least capable (74.09%). The efficiency differences among the Ag NPs treated group; the Laser treated group and the combined MB/Laser treated group were found statistically insignificant.
Conclusion: The combination of MB, 650 nm diode laser and Ag NPs may be among the highly effective modern antimicrobial therapeutics in dentistry.
Databáze: MEDLINE