One-pot chemo-enzymatic conversion of D-xylose to furfuralcohol by sequential dehydration with oxalic acid plus tin-based solid acid and bioreduction with whole-cells.

Autor: Xue XX; Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, PR China., Ma CL; Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, PR China; Hubei Collaborative Innovation Center for Green Transformation of Bio-resources, Hubei Key Laboratory of Industrial Biotechnology, College of Life Sciences, Hubei University, Wuhan, PR China., Di JH; Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, PR China., Huo XY; Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, PR China., He YC; Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, PR China; Hubei Collaborative Innovation Center for Green Transformation of Bio-resources, Hubei Key Laboratory of Industrial Biotechnology, College of Life Sciences, Hubei University, Wuhan, PR China. Electronic address: heyucai2001@163.com.
Jazyk: angličtina
Zdroj: Bioresource technology [Bioresour Technol] 2018 Nov; Vol. 268, pp. 292-299. Date of Electronic Publication: 2018 Aug 01.
DOI: 10.1016/j.biortech.2018.07.152
Abstrakt: In this study, organic acid could be used as co-catalyst for assisting solid acid SO 4 2- /SnO 2 -argil to convert hemicellulose-derived D-xylose into furfural. The relationship between pKa of organic acid and turnover frequency (TOF) of co-catalysis with organic acid plus SO 4 2- /SnO 2 -argil was explored on the conversion of D-xylose to furfural. Oxalic acid (pKa = 1.25) (0.35 wt%) was found to be the optimum co-catalyst for assisting SO 4 2- /SnO 2 -argil (3.6 wt%) to synthesize furfural from D-xylose (20 g/L) at 180 °C for 20 min, and the furfural yield and TOF could be obtained at 57.07% and 6.26 h -1 , respectively. Finally, the obtained furfural (107.6 mM) could be completely biotransformed to furfuralcohol by recombinant Escherichia coli CCZU-K14 whole-cells at 30 °C and pH 6.5 in the presence of 1.5 mol glucose/mol furfural and 400 mM D-xylose. Clearly, this strategy shows high potential application for the effective synthesis of furfuralcohol from biomass-derived D-xylose.
(Copyright © 2018 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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