French infant total diet study: Exposure to selected trace elements and associated health risks.

Autor: Sirot V; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France. Electronic address: sirotv@gmail.com., Traore T; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Guérin T; Université Paris-Est, Anses, Laboratory for Food Safety, F-94701, Maisons-Alfort, France., Noël L; Université Paris-Est, Anses, Laboratory for Food Safety, F-94701, Maisons-Alfort, France; The French Directorate General for Food, Ministry of Agriculture, Agro-Food and Forestry, F-75732, Paris, France., Bachelot M; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Cravedi JP; Toxalim, Université de Toulouse, INRA, INP-ENVT, INP-EI-Purpan, Université de Toulouse Paul Sabatier, Toulouse, France., Mazur A; Université Clermont Auvergne, INRA, UNH, Unité de Nutrition Humaine, CRNH Auvergne, F-63000, Clermont- Ferrand, France., Glorennec P; EHESP-School of Public Health, Sorbonne Paris Cité, Rennes, France; INSERM-U1085, Irset-Research Institute for Environmental and Occupational Health, Rennes, France., Vasseur P; University of Lorraine, CNRS UMR, 7360, Metz, France., Jean J; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Carne G; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Gorecki S; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Rivière G; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France., Hulin M; Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health & Safety (ANSES), 14 rue Pierre et Marie Curie, F-94701, Maisons-Alfort, France.
Jazyk: angličtina
Zdroj: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2018 Oct; Vol. 120, pp. 625-633. Date of Electronic Publication: 2018 Aug 02.
DOI: 10.1016/j.fct.2018.07.062
Abstrakt: A total diet study (TDS) was conducted between 2010 and 2016 to assess the risk associated with chemicals in food of non-breast-fed children under three living in France. 291 composite food samples were prepared "as consumed" and analyzed for 16 trace elements: aluminium (Al), antimony (Sb), arsenic (As), barium (Ba), cobalt (Co), chromium (Cr), gallium (Ga), germanium (Ge), lead (Pb), mercury (Hg), nickel (Ni), silver (Ag), strontium (Sr), tellurium (Te), tin (Sn), vanadium (V). Dietary exposure was assessed for 705 representative children using food consumptions recorded through a 3-consecutive-days record. For inorganic mercury, chromium III, and antimony, the exposure levels were lower than the health-based guidance values and the risk was considered tolerable. Conversely, the exposure levels to inorganic arsenic, lead and nickel were higher than the health-based guidance values for a part of children and were considered as a concern, requiring management measures to reduce the exposure. For aluminium, methylmercury, strontium, chromium VI, cobalt, and barium, a risk could not be ruled out because of uncertainty sources. As a precautionary measure, reducing the exposure is recommended. For chemicals without robust health-based guidance value (organic arsenic, gallium, germanium, silver, tin, tellurium and vanadium), additional data are needed for risk assessment.
(Copyright © 2018 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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